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Synthesis of (±)-2-methyl-6-(3′-hydroxy-4′-methylphenyl)-2-hepten-4-one [turmeronol A]

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Abstract

The first total synthesis of the racemic title compound is described. 3-Hydroxy-4-methyl acetophenone was used as the starting material and transformed into the target molecule in six steps. Synthetic turmeronol A displays spectral properties similar to those reported for the natural compound leading to confirmation of the proposed structure.

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Sharma, M.L., Chand, T. Synthesis of (±)-2-methyl-6-(3′-hydroxy-4′-methylphenyl)-2-hepten-4-one [turmeronol A]. Proc. Indian Acad. Sci. (Chem. Sci.) 109, 177–180 (1997). https://doi.org/10.1007/BF02883487

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  • DOI: https://doi.org/10.1007/BF02883487

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