Abstract
Conserved Ser354, Ser357 in the seventh transmembrane domain of NET were mutated and the function of mutants was studied by3H-NE influx measurement. Double mutation at these two serine sites reduced the activity of NET to base level. It is inferred that these two sites may be involved in the recognition and transport activity of the NET protein.
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Huang, F., Liu, Y., Fei, J. et al. Identification of Ser354 and Ser357 involved in the function of norepinephrine transporter. Chin. Sci. Bull. 43, 1541–1544 (1998). https://doi.org/10.1007/BF02883445
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DOI: https://doi.org/10.1007/BF02883445