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Streptococcal extracellular NAD-glycohydrolase optimal temperature and activation by cysteine

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Abstract

Streptpcoccal extracellular NAD-glycohydrolase (EC 3.2.2.5) exists in two distinct states with respect to the optimal reaction temperature. Bacteria produce the enzyme form with optimum activity at about 40 °C. Probably due to oxygen action, the enzyme is converted to a form with optimum activity at 30 °C. Compounds of the type of cysteine restore the initial state. The conversions are accompanied by enzyme activity fluctuations.

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Zahradník, F.J. Streptococcal extracellular NAD-glycohydrolase optimal temperature and activation by cysteine. Folia Microbiol 22, 92–97 (1977). https://doi.org/10.1007/BF02881633

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