Treatment of arteriosclerosis and vague abdominal distress with niacinamide hydroiodide (without side-effects)

Conclusions

  1. 1)

    The signs and symptoms of “arteriosclerosis” as a clinical entity are reviewed.

  2. 2)

    The beneficial effects of iodide treatment combined with Niacinamide Hydroiodide on the signs and symptoms of arteriosclerosis including vague abdominal distress have been shown.

  3. 3)

    The rationale of the use of an iodide containing the integral portion of the molecule of the co-enzymes to prevent iodism in the form of Niacinamide Hydroiodide is explained.

  4. 4)

    The mechanism of iodism is discussed and correlated with bromism and pellagra as a dysfunction of the co-enzyme oxidation mechanism.

  5. 5)

    Absence of iodism, or any untoward effects from Niacinamide Hydroiodide is shown in a large clinical series treated for over a year.

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References

  1. 1.

    Cecil, R. L. and Kennedy, F.: “Textbook of Medicine,” 6th ed., W. B. Saunders Co., Phila., Penna.

  2. 2.a

    Klump, T. G.: J.A.M.A., 151, 1235.

  3. 2.b

    Klump, T. G., Amer. Jour. Phar., p. 79 (Mar. 1953).

  4. 3.

    MacCallum, W. G.: Physiol. Rev., 2, 70 (1922).

    Google Scholar 

  5. 4.

    Beckman, H. N.: “Pharmacology in Clinical Practice,” W. B. Saunders Co., Phila.,Penna., 1952, p. 205.

    Google Scholar 

  6. 5.

    Goodman, L. and Gilman, A., Pharmacological Basis of Therapeutics, Macmillan Co., 1943, pages 658, 659.

  7. 6.

    Kramer, P., Ingelfinger, F. J.: Use of Antispasmodics and Spasmodics in the Treatment of Gastrointestinal Disorders. Medical Clinics of North America 32, 1227 (1948).

    Google Scholar 

  8. 7.

    Ingelfinger, F. J. and Abbot, W. O.: Intubation Studies of the Human Small Intestine; The Diagnostic Significance of Motor Disturbance, American Journal of Digestive Deseases, 7:468, 1940.

    Google Scholar 

  9. 8.

    Ingelfinger, F. J.: Medical Clinics of North America, Sept. 1943, Boston Number: Treatment of the “Irritable Stomach” and the “Irritable Colon.”

  10. 9.

    Gortner, R. A.: “Outlines of Biochemistry,” 3rd ed., John Wiley & Sons, Inc., New York, 1950, p. 389.

    Google Scholar 

  11. 10.

    Feinblatt, T. M. and Ferguson, E. A.: N. Y. S. Jour, of Med., 52:16, 2017 (1952).

    CAS  Google Scholar 

  12. 11.

    Harris, R. S. and Derian, E. S.: South Med. Jour., 42, 973, 1949.

    Article  CAS  Google Scholar 

  13. 12.

    “II. S. Pharmacopeia,” Vol. 14, Mack Pub. Co., Easton, Penna., 1950, p. 343.

  14. 13.

    Cushney, A. R., Edmunds, C. W. and Gunn, J. A.: “Pharmacology and Therapeutics,” Lea & Febiger, Phila., Penna., 1940, pp. 73–77.

    Google Scholar 

  15. 14.

    Beck, W., Ellinger, P. and Spies, T. D.: Quart. Jour. Med., 6, 305 (1937).

    Google Scholar 

  16. 15.

    Watson, C. J.: Proe. Soc. Exper. Biol. and Med., 39, 514 (1938).

    CAS  Google Scholar 

  17. 16.

    Bray, W. E.: “Synopsis of Clinical Laboratory Methods,” 3rd ed., C. V. Mosby Co., St. Louis, Mo., 1944, p. 59.

    Google Scholar 

  18. 17.

    Spies, T. D., Sasaki, Y. and Cross, E.: South. Med. Jour., 31, 483 (1938).

    Google Scholar 

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Correspondence to Theodore M. Feinblatt or Henry M. Feinblatt or Edgar A. Ferguson.

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Feinblatt, T.M., Feinblatt, H.M. & Ferguson, E.A. Treatment of arteriosclerosis and vague abdominal distress with niacinamide hydroiodide (without side-effects). Amer. Jour. Dig. Dis. 22, 5–6 (1955). https://doi.org/10.1007/BF02881508

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Keywords

  • Arteriosclerosis
  • Untoward Effect
  • Sodium Iodide
  • King County
  • Niacinamide