Conclusions
-
1)
The signs and symptoms of “arteriosclerosis” as a clinical entity are reviewed.
-
2)
The beneficial effects of iodide treatment combined with Niacinamide Hydroiodide on the signs and symptoms of arteriosclerosis including vague abdominal distress have been shown.
-
3)
The rationale of the use of an iodide containing the integral portion of the molecule of the co-enzymes to prevent iodism in the form of Niacinamide Hydroiodide is explained.
-
4)
The mechanism of iodism is discussed and correlated with bromism and pellagra as a dysfunction of the co-enzyme oxidation mechanism.
-
5)
Absence of iodism, or any untoward effects from Niacinamide Hydroiodide is shown in a large clinical series treated for over a year.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Cecil, R. L. and Kennedy, F.: “Textbook of Medicine,” 6th ed., W. B. Saunders Co., Phila., Penna.
Klump, T. G.: J.A.M.A., 151, 1235.
Klump, T. G., Amer. Jour. Phar., p. 79 (Mar. 1953).
MacCallum, W. G.: Physiol. Rev., 2, 70 (1922).
Beckman, H. N.: “Pharmacology in Clinical Practice,” W. B. Saunders Co., Phila.,Penna., 1952, p. 205.
Goodman, L. and Gilman, A., Pharmacological Basis of Therapeutics, Macmillan Co., 1943, pages 658, 659.
Kramer, P., Ingelfinger, F. J.: Use of Antispasmodics and Spasmodics in the Treatment of Gastrointestinal Disorders. Medical Clinics of North America 32, 1227 (1948).
Ingelfinger, F. J. and Abbot, W. O.: Intubation Studies of the Human Small Intestine; The Diagnostic Significance of Motor Disturbance, American Journal of Digestive Deseases, 7:468, 1940.
Ingelfinger, F. J.: Medical Clinics of North America, Sept. 1943, Boston Number: Treatment of the “Irritable Stomach” and the “Irritable Colon.”
Gortner, R. A.: “Outlines of Biochemistry,” 3rd ed., John Wiley & Sons, Inc., New York, 1950, p. 389.
Feinblatt, T. M. and Ferguson, E. A.: N. Y. S. Jour, of Med., 52:16, 2017 (1952).
Harris, R. S. and Derian, E. S.: South Med. Jour., 42, 973, 1949.
“II. S. Pharmacopeia,” Vol. 14, Mack Pub. Co., Easton, Penna., 1950, p. 343.
Cushney, A. R., Edmunds, C. W. and Gunn, J. A.: “Pharmacology and Therapeutics,” Lea & Febiger, Phila., Penna., 1940, pp. 73–77.
Beck, W., Ellinger, P. and Spies, T. D.: Quart. Jour. Med., 6, 305 (1937).
Watson, C. J.: Proe. Soc. Exper. Biol. and Med., 39, 514 (1938).
Bray, W. E.: “Synopsis of Clinical Laboratory Methods,” 3rd ed., C. V. Mosby Co., St. Louis, Mo., 1944, p. 59.
Spies, T. D., Sasaki, Y. and Cross, E.: South. Med. Jour., 31, 483 (1938).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Feinblatt, T.M., Feinblatt, H.M. & Ferguson, E.A. Treatment of arteriosclerosis and vague abdominal distress with niacinamide hydroiodide (without side-effects). Amer. Jour. Dig. Dis. 22, 5–6 (1955). https://doi.org/10.1007/BF02881508
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02881508