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Antimicrobial activity of 3-methyl-5-furfurylidene-2-thioxo-4-thiazolidones

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Abstract

Substituted 3-methyl-5-furfurylidene-2-thioxo-4-thiazolidones1 –17 were tested for their action againstBacillus pumilus, B. brevis andB. megaterium and againstAspergillus flavus, A. fumigatus andA. niger. Most of the compounds possessed an activity against both bacteria and fungi. These compounds were also tested for their effectiveness as virus inhibitors employingNicotiana glutinosa as assay host against tobacco mosaic virus. Most of them exhibited potential antiviral activity bothin vitro andin vivo.

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Authors and Affiliations

  1. Planet Virus Laboratory, Department of Botany, Lucknow University, 226 007, Lucknow, India

    L. P. Awasthi

  2. Division of Biophysics, Central Drug Research Institute, 226 001, Lucknow, India

    S. P. Singh

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  1. L. P. Awasthi
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  2. S. P. Singh
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Awasthi, L.P., Singh, S.P. Antimicrobial activity of 3-methyl-5-furfurylidene-2-thioxo-4-thiazolidones. Folia Microbiol 28, 41–45 (1983). https://doi.org/10.1007/BF02877383

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  • DOI: https://doi.org/10.1007/BF02877383

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