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Antibody formation in young rabbits immunized with erythrocytes

Образование антител после иммунизации крольчат эритроцитами

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Summary

Litters of young rabbits of different ages were immunized with a suspension of foreign erythrocytes. In every case, including rabbits immunized on the first day after birth, antibodies were formed (demonstrated by haemagglutination) on the fifth day after immunization. Age had no influence on the rate of antibody formation. Irradiation of young rabbits with a dose of 350 r. 48 hours prior to immunization inhibited the antibody reaction.

The possible mechanism of this reaction is discussed.

Abstract

Крольчат различного возраста иммунизировали взвесью чуживотных эритроцитов. У всех животных,—даже при иммунизации на первый день после рождения,—наблюдалось образование антител, которое можно было доказать гемагглютинацией уже на 5-й день после иммунизации. Возраст крольчат не оказывал влияния на скорость образования антител. Реакцию образования антител можно было подавить облучением крольчат 350 r за 48 час. до иммунизации.— Обсуждаются возможные механизмы этой реакции.

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Authors and Affiliations

  1. Department of Microbiology, Institute of Biology, Czechoslovak Academy of Sciences, Prague 6

    I. Říha

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  1. I. Říha
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Říha, I. Antibody formation in young rabbits immunized with erythrocytes. Folia Microbiol 6, 355–361 (1961). https://doi.org/10.1007/BF02877176

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  • DOI: https://doi.org/10.1007/BF02877176

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