Folia Microbiologica

, Volume 18, Issue 5, pp 390–392 | Cite as

Ergot alkaloids

IV. Contribution to the biosynthesis of lysergic acid amides
  • E. Kleinerová
  • J. Kybal


Analysis of the fermentation medium during the production phase of submerged cultivation ofClaviceps paspali and model experiments carried out with an authentic sample of lysergic acid α-hydroxy-ethylamide showed that the only native amide produced under the conditions was lysergic acid α-hydroxyethylamide while the simple amide and isomers of the two, including the assumed diastereoisomer of lysergic acid α-hydroxyethylamide, are formed secondarily.


Alkaloid Production Phase Submerged Culture Acid Amide Ergot Alkaloid 
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Copyright information

© Institute of Microbiology, Academy of Sciences of the Czech Republic 1973

Authors and Affiliations

  • E. Kleinerová
    • 1
  • J. Kybal
    • 1
  1. 1.Research Institute for Antibiotics and BiotransformationsRoztoky near Prague

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