Abstract
Evaluation of serum SOD and MDA level was done in 21 first episode renal stone formers, 9 recurrent stone formers, 20 patients with obstructive uropathy other than urolithiasis and 12 patients with urinary infection. Twenty-two healthy volunteers were taken as controls. The level of SOD in respective groups was 2.12±0.84, 2.78±0.85, 1.42±0.31, 1.98±0.70 and 2.32±0.62 units/ml and of MDA was 2.61±1.07, 2.69±1.15, 1.65±0.33, 1.33±0.34 and 1.55±0.48 n mol/ml respectively. The results indicate increased peroxidative stressin nephrolithiasis only. Since SOD level was normal in all groups, this increased peroxidative stress in nephrolithiasis should be due to factors other than this one.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Yoshika Y., Bills T., Jarrett-Moore, T., Green L.H., Burr I.M. and Ichikawa I. (1990) Kidney International, 38: 82.
Freeman, B.A., Capro J.D. (1982) Lab Invest. 47: 412.
Kellog, E.W., Fridovich, I. (1975) J. Biol Chem. 250: 8812.
Anuradha C.V., Selvam, R. (1989) Ind. J. Biochem Biophys, 26: 30.
Biji Kurien, T., Selvam, R. (1989) Ind. J. Exp. Biol. 27: 450.
Fridovich, I., Mishra, H.P. (1972) J. Biol Chem. 247: 3170.
Burge, et. al. (1978) Methods in Enzymology, 52: 306.
Sane, A.S., Chokshi, S.A., Barad, D.P., Shah, V.C., Mathur, V., and Kukreti, S.C. (1989) Ind J. Clin. Biochem. 4: 26.
Sane, A.S., Chokshi, S.A., Mishra, V.V., Barad, D.P., Shah, V.C., Nagpal, S. (1991) Gynecol. Obstet. Invest. 31: 172.
Singh, P.P., Pendse, A.K., Mathur, H.N., (1990) ICMR Project Report-1986–89.
Singh, P.P., and Rajkiran (1993) Scanning Microscopy: 443.
Pendse, A.K., Ghosh, R. Joshi, C.S., Singh, P.P., (1987) Multidimensional Approach to Urolithiasis (Eds Singh P.P. and Pendse A.K., Himanshu Publication, p 149.
Choudhary, M., Rajvanshi, K., Pendse, A.K., and Singh, P.P., (1987) Multidimensional Approach to Urolithiasis. (Eds. Singh P.P., and Pendse A.K., Himanshu Publications, p III.
Sharma, D.C., Khalsa, J.K., Soni, B.L., Singh, P.P. and Simlot, M.M. (1972) J. Ind. Med. Assoc, 58: 204.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Baxi, J., Sharma, K., Rajbala et al. Serum super oxide dismutase (SOD), malondialdehyde (MDA) levels in urinary disorders. Indian J Clin Biochem 9, 47–49 (1994). https://doi.org/10.1007/BF02867856
Issue Date:
DOI: https://doi.org/10.1007/BF02867856