Effect of oral administration of 2 ml per day of suspension (in water) of alcoholic extract of whole fruit of Trichosanthes dioica (2%) (=100 g fresh wt.=7 g dry wt.=1/15 g of alcoholic extract) with the help of catheter alongwith basal diet for four weeks have been studied in the normal albino rabbits. It was observed that this extract lowered the blood sugar, total cholesterol, low density lipoprotein cholesterol and triglyceride levels, and increased the high density lipoprotein cholesterol, phospholipid and faecal sterol levels. Such effects are manifested from the very first week of feeding and are statistically significant.
This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Tax calculation will be finalised during checkout.
Dymock, W., Warden, C.J.H. and Hooper, D. (1891) Pharmacographia Indica, Kegan Paul, Trench, Trubner & Co. LD, London Vol. II, p. 72.
Sharma, G. and Pant, M.C. (1988) Ind. J. Physiol. Pharmac. 32, 161.
Sharma, G. and Pant, M.C. (1988) Ind. J. Med. Res. 87, 398.
Sharma, G. and Pant, M.C. (1988) Current Science 57, 1085.
Sharma, G., Chauhan, S., Pandey, D.N. and Pant, M.C., Agra Univ. J. Res. Sci.-(In Press).
Sharma, G. and Pant, M.C. (1988) Ind. J. Clin. Biochem. (Special Supplement) 3, 15.
Sharma, G. and Pant, M.C. (1988) Proceedings of Annual Conference of U.P. Chapter of Association of Physiologists and Pharmacologists of India, pp. 74.
Carlson, L.A. (1972) Lancet 1, 865.
Nikilla, E.A. and Aro, A. (1973) Lancet 1, 954.
Miller, G.J. and Miller, N.E. (1975) Lancet 1, 16.
I.C.M.R. Bulletin (1986) Division of Publication & Information, ICMR, New Delhi 16 (9), 101.
Mandal, B. (1986) Science Reporter (CSIR, New Delhi, India) 23, 262.
Pharmacopoeia of India (1985) (published by the Controller of publications, Delhi) Vol. II, p. Appendix 3-A, 74.
Somogyi, M. (1952) J. Biol. Chem. 195, 19.
Zlatkis, A., Zak, B. and Boyle, G.J. (1953) J. Lab. Clin. Med. 41, 486.
Burstein, M., Scholnick, H.R. and Morfin, R. (1970) J. Lipid Res. 11, 583.
Friedwald, W.T., Levy, R.T. and Fredrickson, D.S. (1972) Clin. Chem. 18, 499.
Foster, L.B. and Dunn, R.T. (1973) Clin. Chem. 19, 338.
Zilversmith, D.B. and Davis, A.K. (1950) J. Lab. Clin. Med. 35, 155.
Pant, M.C. (1988) Essentials of Biochemistry, 6th Edn. (Published by Kedar Nath Ram Nath & Co., Meerut) pp. 251.
Gordon, T., Castelli, W.P., Hjortland, M.C., Kannel, W.B. and Dawber, T.R. (1977) Amer, J. Med. 62, 707.
Miller, N.E., Forde, O.H., Thelle, D.S. and Mjos, O.D. (1977) Lancet. 1, 965.
About this article
Cite this article
Sharma, G., Pant, M.C. Influence of alcoholic extract of whole fruit of trichosanthes dioica on blood sugar, serum lipids, lipoproteins and faecal sterols in normal albino rabbits. Indian J Clin Biochem 7, 53–56 (1992). https://doi.org/10.1007/BF02867706
- Blood Sugar
- Alcoholic Extract
- Faecal Sterol
- Change Lipid Profile
- Sterol Excretion