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Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency

Abstract

Sixteen weeks of chronic vitamin C deficiency, induced in guinea pigs by restricted vitamin C intake, resulted in a marked increase in the serum total LDL- and VLDL- cholesterol, triglycerides and total lipids. HDL-cholesterol decreased resulting in a highly significant increase in LDL/HDL ratio. The results reconfirm that vitamin C deficiency causes changes in blood lipid profile which could promote atherogenesis.

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Sharma, P., Sharma, P.K., Pramod, J. et al. Hyperlipidemia in guinea pigs induced by chronic vitamin C deficiency. Indian J Clin Biochem 4, 62–64 (1989). https://doi.org/10.1007/BF02867654

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  • DOI: https://doi.org/10.1007/BF02867654

Keywords

  • Total Lipid
  • Deficient Diet
  • Blood Lipid Profile
  • Scurvy
  • Lower Blood Cholesterol