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Effect of preoperative stress on serum lipoperoxide levels


To test the concept of intense psychogenic stress manifesting as organic lesion, effect of pre-operative stress on serum lipid peroxide levels in 30 otherwise healthy patients to undergo major abdominal elective surgery has been studied and compared with healthy controls. Significant elevations in serum lipid peroxide levels both on hospitalization and at pre-operative stage were noticed in comparison with healthy controls. However, serum lipid peroxide levels at pre-operative stage did not show significant fluctuations in comparison with those at the time of admission, suggestive of no probable further increment in autoxidation of unsaturated fatty acids of membrane lipids and proper handling by scavenging enzyme system.

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Sane, A.S., Chokshi, S.A., Barad, D.P. et al. Effect of preoperative stress on serum lipoperoxide levels. Indian J Clin Biochem 4, 26–30 (1989).

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  • Sialic Acid
  • Preoperative Stage
  • Organic Lesion
  • Civil Hospital
  • Serum Lipid Peroxide