Abstract
Rats were fasted for 8 hours and then fed 3 ml of 25% (v/v) ethanol per 100g body weight and subsequently sacrificed 18 hours later. The levels of triacylglycerols and total cholesterol were significantly raised in serum and liver of alcohol fed rats. However, when rats were fed on aqucous extract of onions (300 mg per 100g body weight) with 25% ethanol, no rise in serum and liver lipids was observed. Alcohol fed to the fats with or without onion extract had no effect on serum, AST, ALT and alkaline phosphatase levels. The increase in serum urea in ethanol-fed rats was not altered in rats fed a mixture of alcohol and onion extracts. Values of liver MDA was lower in rats fed ethanol with or without onion extract compared to controls. Onion extract seemed to show a hypolipidemic effect in alcohol fed rats.
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Joseph, J., Dickson, E., Kadam, M.B. et al. Protective role of onion against acute alcoholic fatty liver. Indian J Clin Biochem 6, 27–29 (1991). https://doi.org/10.1007/BF02864961
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DOI: https://doi.org/10.1007/BF02864961