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Synthesis of certain uracil-6-yl or tetrazol-5-ylpyrazolin-5-one and pyrazole derivatives as potential anti-inflammatory agents

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Abstract

Certain pyrazolin-5-one and pyrazole derivatives bearing uracil-6-yl or tetrazol-5-yl moiety in position 1 have been synthesized. The anti-inflammatory activity of six representative compounds have been tested and the results are reported.

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Authors and Affiliations

  1. Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt

    M. A. Moustafa, H. M. Eisa & A. A. El-Emam

  2. Department of Chemistry, Faculty of Sciences, University of Mansoura, Mansoura, Egypt

    M. A. Metwally

Authors
  1. M. A. Moustafa
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  2. H. M. Eisa
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  3. A. A. El-Emam
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  4. M. A. Metwally
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Moustafa, M.A., Eisa, H.M., El-Emam, A.A. et al. Synthesis of certain uracil-6-yl or tetrazol-5-ylpyrazolin-5-one and pyrazole derivatives as potential anti-inflammatory agents. Arch. Pharm. Res. 13, 204–206 (1990). https://doi.org/10.1007/BF02857802

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  • DOI: https://doi.org/10.1007/BF02857802

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