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Thermodynamic study on antibacterial effect of different extracts from Radix Isatis

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Abstract

Objective: To study and analyze the antibacterial effects of different extracts from Radix Isatis.Methods: Staphylococcus aureus was used as the studied object in the experiment. Antibacterial effects of extracts from Radix Isatis were observed by thermocalrimetry on Staphylococcus aureus, together with common pharmacological experiments.Results: The total extract, ethyl acetate (EtOAc) extract,n-butylalcohol (nBuOH) extract, chloroform (CHCl3) extract and petroleum (P.E.) extract had antiviral effects to some extent while the residue after extracting had no antibacterial activity. The potency of antiviral activity among them was as follows: nBuOH extract > EtOAc extract > CHCl3 extract> total extract >P. E. extract.Conclusion: The antibacteriall effects of Radix Isatis were not limited to any active portion, showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways.

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Authors and Affiliations

  1. Institute of Chinese Materia Medica, The 302 Hospital of PLA, 100039, Beijing

    Zhao Yan-ling, Xiao Xiao-he, Liao Qing-wen, Wang Jia-bo, Ma Yong-gang & Sun Yu-qi

  2. Academy of Military Medical Science, China

    Zhao Yan-ling

  3. Clinical Laboratory, the 302 Hospital of PLA, China

    Qu Fen

Authors
  1. Zhao Yan-ling
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  2. Qu Fen
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  3. Xiao Xiao-he
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  4. Liao Qing-wen
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  5. Wang Jia-bo
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  6. Ma Yong-gang
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  7. Sun Yu-qi
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Corresponding author

Correspondence to Zhao Yan-ling.

Additional information

Supported by Foundation of State Administration of Traditional Chinese Medicine (No. 04-05ZP70)

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Yan-ling, Z., Fen, Q., Xiao-he, X. et al. Thermodynamic study on antibacterial effect of different extracts from Radix Isatis. Chin. J. Integr. Med. 12, 42–45 (2006). https://doi.org/10.1007/BF02857429

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  • DOI: https://doi.org/10.1007/BF02857429

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