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Effects of Red ginseng-crude saponin on plasma lipid levels in rats fed on a diet high in cholesterol and triglyceride

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Abstract

The effect of Red ginseng saponin on plasma lipid levels in Wistar rats fed on a diet high in cholesterol and triglyceride was determined. A dose of Red ginseng-crude saponin (150 mg/kg/day) was administered orally for 4 weeks to Wistar rats fed on a diet containing 2% cholesterol and 10% olive oil. Plasma levels of total cholesterol, HDL-cholesterol and triglyceride were measured and lipoproteins were analyzed by using electrophoretic technique. Red ginseng saponin showed no significant changes of HDL-cholesterol level but it lowered plasma levels of total cholesterol and elevate those of triglyceride intensively.

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Authors and Affiliations

  1. College of Pharmacy, Seoul National University, 151, Seoul

    Chang Kiu Moon, Nae Young Kang, Yeo Pyo Yun, Soo Hwan Lee & Hyun Ah Lee

  2. Department of Pharmacy, Dong-Duck Women’s College, 132, Seoul, Korea

    Tak Lim Kang

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  1. Chang Kiu Moon
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  2. Nae Young Kang
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  3. Yeo Pyo Yun
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  4. Soo Hwan Lee
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  5. Hyun Ah Lee
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  6. Tak Lim Kang
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Moon, C.K., Kang, N.Y., Yun, Y.P. et al. Effects of Red ginseng-crude saponin on plasma lipid levels in rats fed on a diet high in cholesterol and triglyceride. Arch. Pharm. Res. 7, 41–45 (1984). https://doi.org/10.1007/BF02856920

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  • DOI: https://doi.org/10.1007/BF02856920

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