Summary
Two to five μ1 20–50% horseradish peroxidase (HRP) in normal saline solution have been injected into the myocardium of the left ventricle of 36 rats. HRP positive reaction granules in spinal ganglion cells have been observed by means of DAB method.
-
1.
The HRP labelled cells were localized in ganglions of the C8-Th8 spinal nerves in 9 rats. This indicates that ganglion cells of the spinal nerves send their peripheral processes as afferent fibers to the left ventricular wall of the heart. The origin of cardiac sympathetic afferent fibers in our experiment showed a much wider distribution than the general range of the Th1-Th5 spinal ganglions. However, the labelled cells contained in Th1-Th5 spinal ganglions amounted to 63.7% in our experiment.
-
2.
The HRP reaction granules contained in spinal ganglion cells were chiefly medium and small in size.
-
3.
The wider origin of cardiac sympathetic afferent fibers provides a possible morphological explanation for referred pain in some cases of angina pectoris.
Similar content being viewed by others
References
Carpenter MB: Human neuroanatomy, ed 7, pp153–162, Williams Co, Baltimore, 1976
Elfvin LG, Dalsgraara CJ: Retrograde axohal transport of horseradish peroxidase in afferent fibers of the inferior mesenteric ganglion of the guinea pig: Identification of the cells of origin in dorsal root ganglia. Brain Res 126: 149, 1977
Neuhuber W, Niederle B: Spinal ganglion cells innervating the stomach of the rat as demonstrated by somatopetal transport of horseradish peroxidase (HRP). Anat Embryol 155(3): 355, 1979
(HRP). 3(1): 97, 1981
Макров ф Н: Исследав aние связей нервной си стемы с помощqyо акосон ого транспора перокс и qDазqy хрена (НRС). Архив А натомиQi гистологий и Э мб-риоqlогиQi 9:108, 1979
1981, 16, 1981
1981, 16, 1981
Hökfelt T, et al: Substance P: Localization in the central nervous system and in some primary sensory neurons. Science 190: 889, 1975
Hökfelt T, et al: Peptidergic neurons. Nature 284: 515, 1980
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Guangqian, L., Yuhua, F. & Jianben, W. Tracing the origin of the sympathetic afferent nerve of the ventriculus cordis by means of horseradish peroxidase method in the rat. Acta Academiae Medicinae Wuhan 3, 147–152 (1983). https://doi.org/10.1007/BF02856648
Issue Date:
DOI: https://doi.org/10.1007/BF02856648