Abstract
A new β-carboline alkaloid, 1-carbobutoxy-β-carboline as well as N9-formylharman, 1-carboethoxy-β-carboline, 1-carbomethoxy-β-carboline, perlolyrine, harman and norharman were isolated from the rhizoma ofPolygala tenuifolia Willdenow. The structures were elucidated on the basis of spectroscopic studies and chemical evidence.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
Takiura, K. and Honda, S.: Sugar Components of the Root ofPolygala tenuifolia.Yakugaku Zasshi,84, 1223 (1964).
Ito, H., Taniguchi, H., Kita, T., Matsukui, Y., Tachikawa, E. and Fujita, T.: Xanthones and a Cinnamic Acid Derivatives fromPolygala tenuifolia.Phytochemistry,16, 1614 (1977).
Sakuma, S. and Shoji, J.: Studies on the Constituents of the Root ofPolygala tenuifolia Willdenow (I), Isolation of Saponins and the Structures of Onjisaponins G. and F.Chem. Pharm. Bull.,29(9), 2431 (1981).
Sakuma, S. and Shoji, J.: Studies on the Constituents of the Root ofPolygala tenuifolia Willenow (II), On the structures of Onjisaponins A,B and E.Chem. Pharm. Bull.,30, 810 (1982).
Kim, J.H.: Studies on the Alkaloid fromPolygala tenuifolia Willdenow.Yakhak Hoeji,8, 59 (1964).
Joshi, B.S., Kamat, V.N. and Gawad, D.H.: Some β-Carboline Alakloids ofAilanthus malabarica DC.Heterocycles,7, 193 (1977).
Chang, Y.K.: Chemical Studies on the Alkaloid Constituents ofCodonopsis lanceolata. Dissertation for Ph.D. Hyosung Women’s University. (1985).
Han, B.H., Park, M.H. Han, Y.N. and Woo, L.K., in press elsewhere.
Jefferys, J. AD.: The Alkaloids of Perennial Rye-Grass (Lolium pernne L.) Part IV, Isolation of a New Base, Perlolyrine, The Crystal Structure of its Hydrobromide Dihydrate, and the Synthesis of the Base,J. Chem. Soc. (C), 1091 (1970).
Snyder, H.R., Walker, H.G. and Werber, F.X.: The Synthesis of β-Carboline V.J. Am. Chem. Soc.,71, 527 (1949).
Achenbach, H. and Biemann, K.: Isotuboflavine and Norisotuboflavine, Two New Alkaloid Isolated fromPleiocarpa mutica Benth.J. Am. Chem. Soc.,87, 4177 (1965).
Ohmoto, T. and Koike, K.: Studies on the Constituents, ofPicrasma quassioides Bennet. I, On the alkaloidal Constituents.Chem. Pharm. Bull.,30, 1204 (1982).
Kermank, W.O., Perkin, W.H. and Robinson, R.: Harmine and Harmaline Part V, The Synthesis of Norharman,J. Chem. Soc.,119, 1602 (1921).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Han, B.H., Park, J.H., Park, M.H. et al. β-Carboline alkaloids ofPolygala tenuifolia . Arch. Pharm. Res. 8, 243–247 (1985). https://doi.org/10.1007/BF02856497
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02856497