Colorectal cancer (CRC) is one of the most common causes of death from cancer in China. During the past twenty years, several case-control studies revealed the high risk factors of CRC in China, which were personal history of intestinal polyp, chronic diarrhea, feces with mucin and blood, psychic attack, drinking of unclear water, operation on appendix, history of chronic constipation and family history of cancer. From these factors, a risk-asessment mode (AD value) was constructed, combined with RPHA-FOB, a mass screening mode was established and applied into common people, awarded with a good result. The population-based CRC prevention including randomized trial has been conducted in two fields (Haining city and Jiashan city in Zhejiang province), which demonstrated that removal of CRC pre-cancer lesions such as adenomas and polyps could reduce CRC incidence and mortality remarkably.
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This project was supported by grants from foundations of National “Seventh-five” (No. 75-61-02-17), “Eighth-five” (No. 85-914-01-09) key projects and Ministry of public Health of China (No. 981335).
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Shu, Z., Shanrong, C. Colorectal cancer epidemiology and prevention study in China. Chin. -Ger. J. Clin. Oncol. 2, 72–75 (2003). https://doi.org/10.1007/BF02855647
- colorectal cancer
- mass screening
- risk factors