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Effects of smoking on periodontal health: A review

Advances in Therapy volume 17, pages 230–237 (2000)Cite this article

Abstract

Cigarette smoking is a risk factor for several diseases, and recent evidence strongly suggests an adverse effect on periodontal health. Nevertheless, the nature of the relationship between smoking and periodontal disease is not clear. Smoking causes defects in neutrophil function, impairs inflammatory and immune responses to periodontal pathogens, and exerts both systemic and local effects. Smoking is associated with an increased rate of periodontal disease in terms of alveolar bone loss and attachment loss, as well as pocket formation. Nicotine, the major component of cigarette smoke, may weaken host defenses to the bacterial invasion induced by plaque.

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References

  1. Ismaïl A, Burt B, Eklund S. Epidemiology patterns of smoking and periodontal disease in the US.J Am Dent Assoc. 1983;106:617–621.

    PubMed  Google Scholar 

  2. Baab D, Öberg P. The effect of cigarette smoking on gingival blood flow in humans.J Clin Periodontol. 1987;14:418–424.

    Article  PubMed  CAS  Google Scholar 

  3. Bergström J, Persson 1, Preber H. Influence of cigarette smoking on vascular reaction during experimental gingivitis.Scand J Dent Res. 1988;96:34–39.

    PubMed  Google Scholar 

  4. Kardachi BR, Clarke NG. Aetiology of acute necrotizing ulcerative gingivitis: a hypothetical explanation.J Periodontol. 1974;45:830–832.

    PubMed  CAS  Google Scholar 

  5. Walter CPT, Shieds D. Acute necrotizing ulcerative gingivitis. A study of some of the contributing factors and their validity in an army population.J Periodontol. 1979;50:146–147.

    Google Scholar 

  6. Modeer T, Lavstedt S, Aeklund C. Relation between tobacco consumption and oral health in Swedish schoolchildren.Acta Odontol Scand. 1980;38:223–227.

    Article  PubMed  CAS  Google Scholar 

  7. Preber H, Kant T, Bergström J. Cigarette smoking, oral hygiene and periodontal health in Swedish army conscripts.J Clin Periodontol. 1980;7:106–113.

    Article  PubMed  CAS  Google Scholar 

  8. Feldman R, Bravacos J, Rose C. Association between smoking different tobacco products and periodontal disease indexes.J Periodontol. 1983;54:481–487.

    PubMed  CAS  Google Scholar 

  9. Bergström J, Floderus-Myrhed B. Study of the relationship between smoking and some periodontal disease factors.Commun Dent Oral Epidemiol. 1983;11:113–116.

    Article  Google Scholar 

  10. Preber H, Bergström J. Occurrence of gingival bleeding in smoker and non-smoker patients.Acta Odontol Scand. 1985;43:315–320.

    Article  PubMed  CAS  Google Scholar 

  11. Palmer R. Tobacco smoking and oral health: a review.Br Dent J. 1988;164:258–260.

    Article  PubMed  CAS  Google Scholar 

  12. Danielsen B, Manji F, Nagelkerke N, Baelum V. Effect of cigarette smoking on the transition dynamics in experimental gingivitis.J Clin Periodontol. 1990;17:159–164.

    Article  PubMed  CAS  Google Scholar 

  13. Hodge PJ, Teague PW, Wright AF, Kinane DF. Clinical and genetic analysis of a large north European Caucasian family affected by early-onset periodontitis.J Dent Res. 2000;79:857–863.

    Article  PubMed  CAS  Google Scholar 

  14. Goultschin J, Cohen H, Donchin M, Brayer 1, Soskolne W. Association of smoking with periodontal treatment needs.J Periodontol. 1990;61:364–367.

    PubMed  CAS  Google Scholar 

  15. Bercy P, Meurisse JB, Lambert ML, Tonglet R. Application of the CPITN in a group of 35–65 year old Belgian employees: comparison with different parameters.J Dent Res. 1998;(special issue B):831.

  16. Genco R. Current view of risk factors for periodontal diseases.J Periodontol. 1996;67(suppl):1041–1049.

    PubMed  CAS  Google Scholar 

  17. Kaldahl W, Johnson G, Patil K, Kalkwarf K. Levels of cigarette consumption and response to periodontal therapy.J Periodontol. 1996;67:675–681.

    PubMed  CAS  Google Scholar 

  18. Martinez-Canut P, Benlloch D, Izquierdo R. Factors related to the quantity of subgingival calculus in proximal root surfaces.J Clin Periodontol. 1999;26:519–524.

    Article  PubMed  CAS  Google Scholar 

  19. Wactawski-Wende J, Wactawski-Wende AL. The role of osteopenia in oral bone loss and periodontal disease.J Periodontol. 1996;67(suppl 10):1076–1084.

    PubMed  CAS  Google Scholar 

  20. Mullally B, Linden G. Molar furcation involvement associated with cigarette smoking in periodontal referrals.J Clin Periodontol. 1996;23:658–661.

    Article  PubMed  CAS  Google Scholar 

  21. Wang HL, Burgert FG, Shyr Y, Ramfjord S. The influence of molar furcation involvement and mobility on future clinical periodontal attachment loss.J Periodontol. 1994;65:25–29.

    PubMed  CAS  Google Scholar 

  22. Linden G, Mullally B. Cigarette smoking and periodontal destruction in young adults.J Periodontol. 1994;65:718–723.

    PubMed  CAS  Google Scholar 

  23. Haber J, Kent R. Cigarette smoking in a periodontal practice.J Periodontol. 1992;63:100–106.

    PubMed  CAS  Google Scholar 

  24. Bergstrom J, Eliasson S, Dock J. Exposure to tobacco smoking and periodontal health.J Clin Periodontol. 2000;27:61–68.

    Article  PubMed  CAS  Google Scholar 

  25. Martinez-Canut P, Lorca A, Magan R. Smoking and periodontal disease severity.J Clin Periodontol. 1995;22:743–749.

    Article  PubMed  CAS  Google Scholar 

  26. Söder B, Söder P, Frithiof L, Lavstedt S, Engström P. Effect of smoking tobacco on the severity of periodontal disease.J Dent Res. 1990;189:647. Abstract.

    Google Scholar 

  27. Machuca G, Rosales I, Lacalle JR, Machuca C, Bullon P. Effect of cigarette smoking on periodontal status of healthy young adults.J Periodontol. 2000;71:73–78.

    Article  PubMed  CAS  Google Scholar 

  28. Johnson G, Kaldahl W, Patil K, Kalkwarf K. The effect of smoking on the response to periodontal therapy.J Clin Periodontol. 1994;21:91–97.

    Article  PubMed  Google Scholar 

  29. Axelsson P, Paulander J, Lindhe J. Relationship between smoking and dental status in 35-, 50-, 65-, and 75-year-old individuals.J Clin Periodontol. 1998;25:297–305.

    Article  PubMed  CAS  Google Scholar 

  30. Grossi S, Zambon J, Ho AW, et al. Assessment of risk for periodontal disease, I: risk indications for attachment loss.J Periodontol. 1994;65:260–267.

    PubMed  CAS  Google Scholar 

  31. Kerdvongbundit V, Wikesjo UM. Effect of smoking on periodontal health in molar teeth.J Periodontol. 2000;71:433–437.

    Article  PubMed  CAS  Google Scholar 

  32. Rivera-Hidalgo F. Smoking and periodontal disease.J Periodontol. 1986;57:617–624.

    PubMed  CAS  Google Scholar 

  33. Preber H, Linder 1, Bergström J. Periodontal healing and periopathogenic microflora in smokers and non-smokers.J Clin Periodontol. 1995;22:946–952.

    Article  PubMed  CAS  Google Scholar 

  34. Preber H, Bergström J. Cigarette smoking in patients referred for periodontal treatment.Scand J Dent Res. 1986;94:102–108.

    PubMed  CAS  Google Scholar 

  35. Bergström J, Eliasson S. Noxious effect of cigarette smoking on periodontal health.J Periodont Res. 1987;22:513–517.

    Article  PubMed  Google Scholar 

  36. Beck JD, Koch GG, Rozier RG, Tudor GE. Prevalence and risk indicators for periodontal attachment loss in a population of older community-dwelling blacks and whites.J Periodontol. 1990;61:521–528.

    PubMed  CAS  Google Scholar 

  37. Bergström J, Eliasson S, Preber H. Cigarette smoking and periodontal bone loss.J Periodontol. 1991;62:242–246.

    PubMed  Google Scholar 

  38. Haber J, Wattles J, Crowley M, Mandell R, Joshipura K, Kent R. Evidence for cigarette smoking as a major risk factor for periodontitis.J Periodontol. 1993;64:16–23.

    PubMed  CAS  Google Scholar 

  39. Wouters FR, Salonen LWE, Frithiof L, Hellden LB. Significance of some variables on interproximal alveolar bone height based on cross-sectional epidemiologic data.J Clin Periodontol. 1993;20:199–206.

    Article  PubMed  CAS  Google Scholar 

  40. Grossi SG, Zambon J, Ho AW. Assessment of risk for periodontal disease, II: risk indicators for alveolar bone loss.J Periodontol. 1995;66:23–29.

    PubMed  CAS  Google Scholar 

  41. Schenkein HA, Gunsolley JC, Koertge TE, Schenkein JG, Tew JG. Smoking and its effects on early-onset periodontitis.J Am Dent Assoc. 1995;126:1107–1113.

    PubMed  CAS  Google Scholar 

  42. Tonetti M, Pini-Prato G, Cortellini P. Effect of cigarette smoking on periodontal healing following GTR in infrabony defects.J Clin Periodontol. 1995;22:229–234.

    Article  PubMed  CAS  Google Scholar 

  43. Cortellini P, Pini-Prato GP, Tonetti MS. Long-term stability of clinical attachment following GTR and conventional therapy.J Clin Periodontol. 1996;23:106–111.

    Article  PubMed  CAS  Google Scholar 

  44. Bergström J. Tobacco smoking and supragingival dental calculus.J Clin Periodontol. 1999;26:541–547.

    Article  PubMed  Google Scholar 

  45. Swenson H. The effect of cigarette smoking on plaque formation.J Periodontol. 1977;50:146–147.

    Google Scholar 

  46. MacGregor I, Edgar W, Greenwood A. Effects of cigarette smoking on the rate of plaque formation.J Clin Periodontol. 1985;12:35–41.

    Article  PubMed  CAS  Google Scholar 

  47. Preber H, Bergström J, Linder L. Occurrence of periopathogens in smoker and non-smoker patients.J Clin Periodontol. 1992;19:667–671.

    Article  PubMed  CAS  Google Scholar 

  48. Zuabi O, Machtei EE, Ben-Aryeh H, Ardekian L, Peled M, Laufer D. The effect of smoking and periodontal treatment on salivary composition in patients with established periodontitis.J Periodontol. 1999;70:1240–1246.

    Article  PubMed  CAS  Google Scholar 

  49. Armitage AK, Dollery CT, George CF, Houseman TH, Lewis PJ, Turner DM. Absorption and metabolism of nicotine from cigarettes.Br Med J. 1975;4:313–316.

    PubMed  CAS  Google Scholar 

  50. Payne J, Johnson G, Reinhardt R, Dyer J, Maze C, Dunning D. Nicotine effects on PGE2 and I-1β release by LPS-treated human monocytes.J Periodont Res. 1996;31:99–104.

    Article  PubMed  CAS  Google Scholar 

  51. Stookey G, Katz B, Olson B, Drook C, Cohen S. Evaluation of biochemical validation measures in determination of smoking status.J Dent Res. 1987;66:1597–1601.

    PubMed  CAS  Google Scholar 

  52. Bostrom L, Linder LE, Bergstrom J. Smoking and GCF levels of IL-1 beta and IL-1RA in periodontal disease.J Clin Periodontol. 2000;27:250–255.

    Article  PubMed  CAS  Google Scholar 

  53. Cuff MJ, McQuade MJ, Scheidt NJ, Sutherland DE, Van Dyke TE. The presence of nicotine on root surfaces of periodontally diseased teeth in smokers.J Periodontol. 1989;60:564–569.

    PubMed  CAS  Google Scholar 

  54. Chappie IL. C reactive oxygen species and antioxidants in inflammatory diseases.J Clin Periodontol. 1997;24:287–296.

    Article  Google Scholar 

  55. Raulin LA, McPherson JC, McQuade MJ, Hanson BS. The effect of nicotine on the attachment of human fibroblasts on glass and human root surfaces in vitro.J Periodontol. 1988;59:318–325.

    PubMed  CAS  Google Scholar 

  56. Tipton D, Dabbous M. Effects of nicotine on proliferation and extracellular matrix production of human gingival fibroblasts in vitro.J Periodontol. 1995;66:1056–1064.

    PubMed  CAS  Google Scholar 

  57. Preber H, Bergström J. Effect of cigarette smoking on periodontal healing following surgical therapy.J Clin Periodontol. 1990;17:324–328.

    Article  PubMed  CAS  Google Scholar 

  58. Johnson GK, Poore TK, Payne J, Organ C. Effect of smokeless tobacco extract on human gingival keratinocyte levels of PGE2 and IL-1β.J Periodontol. 1996;67:116–124.

    PubMed  CAS  Google Scholar 

  59. Offenbach SS, Odle BM, Van Dyke TE. The use of crevicular fluid PGE2 levels as a predictor of periodontal attachment loss.J Periodont Res. 1986;21:101–112.

    Article  Google Scholar 

  60. Stashenko P, Fujiyoshi P, Obernesser MS, Prostak L, Haffajee AD, Socransky SS. Levels of interleukin 1β from sites of active periodontal disease.J Clin Periodontol. 1991;18:548–554.

    Article  PubMed  CAS  Google Scholar 

  61. Pauletto NC, Liede K, Nieminen A, Larjava H, Uitto VJ. Effect of cigarette smoking on oral elastase activity in adult periodontitis patients.J Periodontol. 2000;71:58–62.

    Article  PubMed  CAS  Google Scholar 

  62. Macfarlane G, Herzberg M, Wolff L, Hardie N. Refractory periodontitis associated with abnormal polymorphonuclear leukocyte phagocytosis and cigarette smoking.J Periodontol. 1992;63:908–913.

    PubMed  CAS  Google Scholar 

  63. Poore TK, Johnson GK, Reinhardt RA, Organ CC. The effects of smokeless tobacco on clinical parameters of inflammation and gingival crevicular fluid PGE2-IL1A and IL1β.J Periodontol. 1995;66:177–183.

    PubMed  CAS  Google Scholar 

  64. McCann D. Tobacco use and oral health.J Am Dent Assoc. 1989;118:18–25.

    PubMed  CAS  Google Scholar 

  65. Grossi SG, Skrepcinski FB, De Caro T, et al. Response to periodontal therapy in diabetics and smokers.J Periodontol. 1996;67(suppl):1094–1102.

    PubMed  CAS  Google Scholar 

  66. Pabst MJ, Pabst KM, Collier JA, et al. Inhibition of neutrophil and monocyte defensive functions by nicotine.J Periodontol. 1996;66:1047–1055.

    Google Scholar 

  67. Luepke P, Mellonig J, Brunsvold M. A clinical evaluation of a bioresorbable barrier with and without decalcified freeze-dried bone allograft in the treatment of molar furcations.J Clin Periodontol. 1997;24:440–446.

    Article  PubMed  CAS  Google Scholar 

  68. Rosen P, Marks M, Reynolds M. Influence of smoking on long-term clinical results of intrabony defects treated with regenerative therapy.J Periodontol. 1996;67:1159–1163.

    PubMed  CAS  Google Scholar 

  69. Haber J. Smoking is a major risk factor for periodontitis.Curr Opin Periodontol. 1994;January:12–18.

    Google Scholar 

  70. Brochut PF, Cimasoni G. Tabagisme et parodonte, I: historique et aspects cliniques.Schweiz Monatsschr Zahnmed. 1997;107:673–680.

    Google Scholar 

  71. Sees K. Cigarette smoking, nicotine dependence and treatment.West J Med. 1990;152:578–584.

    PubMed  CAS  Google Scholar 

  72. Cooper M, Clayton R. Stop-smoking program using nicotine reduction therapy and behavior modification for heavy smokers.J Am Dent Assoc. 1989;118:47–50.

    PubMed  CAS  Google Scholar 

  73. MacGregor IDM. Efficacy of dental health advice as an aid to reducing cigarette smoking.Br Dent J. 1996;180:292–296.

    Article  PubMed  CAS  Google Scholar 

  74. Schroeder KL, Soller HA, Chen MS Jr, Neal CJ, Glover ED. Screening for smokeless tobacco-associated lesions.J Am Dent Assoc. 1988;116:37–42.

    PubMed  CAS  Google Scholar 

  75. Gerbert B, Richard R, Coates T, Cunnings S, Zahnd E. Dentists as smoking cessation counselors.J Am Dent Assoc. 1989;118:29–32.

    PubMed  CAS  Google Scholar 

  76. Geboy M. Dentist’s involvement in smoking cessation counseling: a review and analysis.J Am Dent Assoc. 1989;118:79–83.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. School of Dental Medicine and Stomatology, Department of Periodontology, Catholic University of Louvain, Avenue Hippocrate, No. 15, 1200, Brussels, Belgium

    Patrick Obeid D.D.S. & P. Bercy D.D.S., Ph.D.

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  1. Patrick Obeid D.D.S.
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  2. P. Bercy D.D.S., Ph.D.
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Obeid, P., Bercy, P. Effects of smoking on periodontal health: A review. Adv Therapy 17, 230–237 (2000). https://doi.org/10.1007/BF02853162

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