Abstract
Objective To observe the therapeutic effects and action mechanism of moxibustion in the treatment of intestinal fibrosis in ulcerative colitis.Methods Tianshu (ST25) and Qihai (CV6) were the main acupoint; other points were used according to syndrome differentiation. Sixty-five patients were randomized into two groups: Group A in which 32 cases were treated by herbpartitioned moxibustion and group B in which 33 cases were treated by bran-partitioned moxibustion. The therapeutic effects and TGF-β1, I and III collagen expressions were measured before and after treatment.Results
In group A, 17 cases were cured, 12 cases improved and 3 failed; in group B, 11 cases were cured, 16 cases improved and 6 cases failed. I, III collagen expressions were obviously inhibited in the two groups, in group A in particular.Conclusion In the prevention and treatment of intestinal fibrosis, moxibustion may reduce the expression of TGF-β1, and hence to block or inhibit the synthesis of I, III collagens, and improve the structure and function.
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Foundation Item: This study supported by the National Natural Science Foundation of China, No.39970922, and Shanghai Science and Technology Committee and State Administration Bureau of Traditional Chinese Medicine
Translator: XIAO Yuan-chun
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Huan-gan, W., Guang-qing, A., Hui-rong, L. et al. Clinical study on the prevention and treatment of intestinal fibrosis in ulcerative colitis by moxibustion. J. Acupunct. Tuina. Sci. 1, 14–17 (2003). https://doi.org/10.1007/BF02850937
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DOI: https://doi.org/10.1007/BF02850937