Managing childhood atopic dermatitis

Abstract

Atopic dermatitis, a chronic inflammatory skin disorder that affects up to 20% of school-aged children, can profoundly influence quality of life. Basic therapy consists of avoidance of triggering factors and optimal skin care. Until now, corticosteroids have been the usual treatment for acute flares. Short-term safety profiles are reasonable, but long-term use of corticosteroids may involve significant adverse effects. Topical immunomodulators (tacrolimus and pimecrolimus) are beneficial and safe for adults and children and represent a major new alternative to chronic cortico-steroid use, especially in children.

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Correspondence to Alexander K. C. Leung MBBS, FRCP.

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Leung, A.K.C., Barber, K.A. Managing childhood atopic dermatitis. Adv Therapy 20, 129–137 (2003). https://doi.org/10.1007/BF02850199

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Keywords

  • atopic dermatitis
  • children
  • immunomodulator
  • tacrolimus
  • pimecrolimus