Advances in Therapy

, Volume 24, Issue 1, pp 161–170

Initial clinical experience with the trabecular micro-bypass stent in patients with glaucoma

  • Detlev Spiegel
  • Wolfgang Wetzel
  • David S. Haffner
  • Richard A. Hill

DOI: 10.1007/BF02850004

Cite this article as:
Spiegel, D., Wetzel, W., Haffner, D.S. et al. Adv Therapy (2007) 24: 161. doi:10.1007/BF02850004


This study was undertaken to evaluate the efficiency of a trabecular micro-bypass stent designed to allow direct aqueous drainage from the anterior chamber into Schlemm’s canal in patients with glaucoma. In this prospective case series of 6 patients with open-angle glaucoma, the microstent was inserted ab interno under local anesthesia in an ophthalmic operating room. Patients were seen postoperatively at 1 to 2 d, 1 wk, and 1, 2, 6, and 12 mo. All stents were successfully placed within Schlemm’s canal. Mean intraocular pressure (IOP) at preoperative baseline was 20.2±6.3 mm Hg (range, 14–31 mm Hg). Mean IOP decreased during the immediate postoperative period to approximately 12 to 13 mm Hg and was stabilized at 14 to 15 mm Hg with reduction of medication throughout 1 y of follow-up. No major complications occurred. According to observations reported in this feasibility study, the microstent was effective in reducing IOP and in decreasing the number of glaucoma medications required to control IOP. Implantation procedures were safe, and stents remained in place throughout the follow-up period. None of the complications traditionally associated with filtering surgery were reported. Further research on this stent in a larger group of patients is needed to assess its role in glaucoma therapy.


glaucoma stents trabecular surgery intraocular pressure glaucoma therapy trabecula 

Copyright information

© Health Communications Inc 2007

Authors and Affiliations

  • Detlev Spiegel
    • 1
  • Wolfgang Wetzel
    • 2
  • David S. Haffner
    • 3
  • Richard A. Hill
    • 4
  1. 1.Klinik VincentinumAusburgGermany
  2. 2.Private PracticeWeinheimGermany
  3. 3.Glaukos CorporationLaguna Hills
  4. 4.Orange County GlaucomaSanta Ana
  5. 5.Glaukos CorporationLaguna Hills

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