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Newer concepts and approaches to neonatal brain asphyxia

  • Symposium: Advances in Neonatology — I
  • Published:
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Abstract

The asphyxial injury to neonate brain seems to be mediated through a cascade of biochemical events during ischaemia—reperfusion which includes excitatory amino acids, free radicals and accelerated programmed cell death (Apoptosis). The diagnosis of asphyxia requires rigorous approach based on background clinical information, certain diagnostic tests and exclusion of alternative diagnosis which may have similar clinical presentation. The treatment currently employed for the management of birth asphyxia controversial and requires critical appraisal. The future strategies for management include a number of approaches based on putative mechanism for asphyxial brain injury but they are still being evaluated as research and should not be used for clinical purposes in human newborns as yet.

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Authors and Affiliations

  1. Directorate of Neonatology, Division of Women and Children, South Cleveland Hospital, TS4 3BW, Middlesbrough, Cleveland, UK

    Sunil K. Sinha (Director) & Jaideep Singh

Authors
  1. Sunil K. Sinha
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  2. Jaideep Singh
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Sinha, S.K., Singh, J. Newer concepts and approaches to neonatal brain asphyxia. Indian J Pediatr 65, 55–62 (1998). https://doi.org/10.1007/BF02849695

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  • DOI: https://doi.org/10.1007/BF02849695

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