“… He was particularly glad that she always put her victim to sleep before eating it … ‘Yes’, she replied in her sweet musical voice, ‘I always give them an anaesthetic so they won't feel pain. It's a little service I throw in!’”Charlotte A. Cavatica from,Charlotte's Web, by E.B. White, 1952
Abstract
For many years pediatric procedural and postoperative pain has been undertreated or not treated. In some areas this practice still exists and is a likely reflection of persistence of myths related to the infant's ability to perceive pain. Such myths include the lack of ability to perceive pain or remember painful experiences. New literature exists showing that these former beliefs do not hold true. The appropriate management of postoperative pain is contingent on a cooperative effort from pediatric surgeons, pediatric anesthesiologists, pediatricians, and parents. There are many ways to treat postoperative pain. The method of postoperative analgesia depends on the patient, underlying medical conditions, the type of surgery, the patient's disposition following surgery (inpatient vs. outpatient), and the physician's comford level with a particular analgesic regimen. Many pediatric anesthesiologists and surgeons have excellent success with the utilization of regional anesthetic techniques as treatment for postoperative pain. Caudal epidural blocks, ilioinguinal/iliohypogastric nerve blocks, and penile nerve blocks are some of the commonly used blocks. These blocks not only provide excellent postoperative analgesia, but are great adjuncts to general anesthesia, thus, reducing the amount of general anesthesia required. Additionally, the use of epidural opioids is extremely useful in patients following major abdominal, thoracic, and orthopedic surgery. Traditional medications such as oral and parenteral narcotics, non-steroidal anti-inflammatory drugs, and acetaminophen (paracetamol), are much more commonly used to treat postoperative pain. Regardless of the analgesic regimen chosen, we must assure our pediatric patients the least painful perioperative experience possible.
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References
Anand KJS, Hickey PR. Halothanemorphine compared with high dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery.N Engl J Med 1992; 326: 1–9.
Anand KJS, Hansen DD, Hickey PR. Hormonal-metabolic stress responses in neonates undergoing cardiac surgery.Anesthesiology 1990; 73: 661–70.
Anand KJS, Hickey PR. Pain and its effects on the human neonate and fetus.N Engl. J Med 1987; 317: 1321–29.
Williamson PS, Williamson ML. Physiologic stress reduction by a local anesthetic during newborn circumcision.Pediatrics 1983; 71: 36–40.
Schechter NL, Berde CB, Yaster M. Pain in infants, children, and adolescents: An overview. In: Schechter NL, Berde CB, Yaster M' ed.Pain in Infants, Children and Adolescents, Baltimore: Williams and Wilkins, 1993; 3–7.
Swafford L, Allen D. Pain relief in the pediatric patient.Med Clin North Am 1968; 52: 131–136.
Eland JM, Anderson JE. The experience of pain in children. In: Jacox A, ed.Pain: A Source Book for Nurses and Other Health Professionals., Boston: Little Brown, 1977.
Mather L, Mackie J. The incidence of postoperative pain in children.Pain 1983; 15: 271–282.
Beyer JE, Degood DE, Ashely LC, Russell GA. Patterns of postoperative analgesic use with adults and children following cardiac surgery.Pain 1983; 17: 71–81.
Schechter NL, Bernstein BA, Beck A, Hart L, Scherzer L. Individual differences in children's response to pain: role of temperament and parental characteristics.Pediatrics 1991; 87: 171–177.
Anand KJS, Sippell WG, Aynsley-Green A. Randomized trial of fentanyl anesthesia in preterm babies undergoing surgery: effects on stress response.Lancet 1987; 1: 243–248.
Anand KJS, Carr DB, Hickey PR. Randomized trial of high dose sufentanil anesthesia in neonates undergoing cardiac surgery: hormonal and hemodynamic stress responses.Anesthesiology 1987; 67: A501.
Brown R, Broadman LM. Patient-controlled analgesia (PCA) for postoperative pain control in adolescents.Anesth Analg 1987; 66: S22.
Romsing J, Walther-Larsen S. Postoperative pain in children: A survey of parents' expectations and perceptions of their children's experiences.Pediatric Anaesthesia 1996; 6: 215–218.
Knight JC. Postoperative pain in children after day case surgery.Pediatric Anaesthesia 1994; 4: 45–51.
Finely GA, McGrath PJ, Forward SP, McNeill Gm, Fitzgerald P. Parent's management of children's pain following ‘minor’ surgery.Pain 1996; 64: 83–87.
Hannallah RS, Broadman LM, Belman AS Abramowitz MD, Epstein BS. Comparison of caudal and ilioinguinal/iliohypogastric nerve blocks for control of post-orchiopexy pain in pediatric ambulatory surgery.Anesthesiology 1987; 66: 832–834.
McGrath PJ, Johnson Gm, Goodman JT, Schillinger J, Dunn J, Champman JA. CHEOPS: A behavioral pain scale for rating postoperative pain in children.Advances in Pain Research and Therapy 1985; 9: 395–402.
Krechel SW, Bildner J. CRIES: A new neonatal postoperative pain management score. Initial testing of validity and reliability.Pediatric Anaesthesia 1995; 5: 53–61.
Campbell MF. Caudal anesthesia in children.Journal of Urology 1933; 30: 245.
Ecoffey C, Desparmet J, Maury M. Bupivicaine in children: Pharmacokinetics following caudal anesthesia.Anesthesiology 1985; 63: 447–448.
Ecoffey C, Desparmet J, Berdeaus A. Pharmacokinetics of lignocaine in children following caudal anesthesia.Br J Anaesth 1984; 56: 1399–1402.
McGown RG. Caudal analgesia in children (500 cases for procedures below the diaphragm).Anaesthesia 1982; 37: 806–818.
Spear RM, Deshpande J, Maxwell L. Caudal anesthesia in the awake, high-risk infant.Anesthesiology 1988; 69: 407–409.
Henderson KH, Sethna NF, Berde CB. Continuous caudal anesthesia for inguinal hernia repair in former preterm infants.J Clin Anesth 1993; 5(2): 129–133.
Takasaki M, Dohi S, Kawabata Y, Takahashi T. Dosage of lidocaine for caudal anesthesia in infants and children.Anesthesiology 1977; 47: 527–529.
Armitage EN. Caudal block in children.Anesthesia 1979; 34: 396–405.
Murat I, Delleur MM, Esteve C, Egu JF, Raynaud P, Saint-Mauric C. Continuous epidural anesthesia in children: Clinical and hemodynamic implications.Br J Anaesth 1987; 59: 1441.
Warner MA, Kunkel SE, Offored KO, Atchison SR, Dawson B. The effects of age, epinephrine, and operative site on duration of caudal analgesia in pediatric patients.Anesth Analg 1987; 86: 995.
Saint Mauric C, Steinberg OS.Regional Anesthesia in Children. Norwalk: Appleton & Lang/Mediglobe, 1990: 155–156.
Steward DJ. Preterm infants are more prone to complications than are term infants.Anesthesiology 1982; 56: 304–306.
Steward DJ, Gregory GA. Life-threatening perioperative apnea in the ex-“premie”.Anesthesiology 1983; 59: 495–498.
Kurth CD, LeBard SE. Association of postoperative apnea, airway obstruction and hypoxemia in former preterm infantsAnesthesiology 1991; 75: 22–26.
Abajian JC, Mellish RWP, Browne AF, Perkins FM, Lambert DH, Mazuzan JE. Spinal anesthesia for surgery in the high risk infant.Anesth Analg 1984; 63: 359–362.
Welborn LG, Rice LJ, Hannallah RS, Broadman LM, Ruttimann UE, Fink R. Postoperative apnea in former preterm infants: Prospective comparison of spinal and general anesthesia.Anesthesiology 1990; 72: 838–842.
McDonald TB, Berkowtiz RA. Single dose and continuous microcatheter spinal anesthesia in former preterm infants.Anesthesiology 1991; 75: A911.
Harnik EV, Hoy GR, Potolicchio S, Stewart DR, Siegelman RE. Spinal anesthesia in premature infants recovering from respiratory distress syndrome.Anesthesiology 1986; 64: 95–99.
Blasie GA, Roy WL. Spinal anesthesia in children.Anesth Analg 1984; 63: 1140–1141.
Kahana MD. Acute pain management in children. In: Berry FA, ed.Anesthetic Management of Difficult and Routine Pediatric Patients, New York: Churchill Livingstone, 1990: 323–340.
Kirya C, Werthmann MW. Neonatal circumcision and penile dorsal nerve block—a painless procedure.J Pediatr 1978; 92: 998–1000.
Maxwell LG, Yaster M, Wetzel RC, Niebyl JR. Penile block for newborn circumcisionObstet Gynecol 1987; 70: 415–419.
Yeoman PM, Cooke R, Hain WR. Penile block for circumcision? A comparison with caudal blockade.Anaesthesia 1983; 38: 862–866.
Broadman L, Hannallah RS, Belman AB, Elder PT, Ruttimann U, Epstein BS. Post circumcision analgesia—a prospective evaluation of subcutaneous ring block of the penis.Anesthesiology 1987; 67: 399–402.
Yaster M, Maxwell LG. Pediatric regional anesthesia (Review).Anesthesiology 1989; 70: 324–338.
Rusy LM, Houck CS, Sullivan LJet al. A double blind evaluation of ketorolac tromethamine versus acetaminophen in the pediatric tonsillectomy patient. Effects on analgesia and bleeding.Anesth Analg 1995; 80: 226–229.
Montgomery CJ, McCormack JP, Reichert CC, Marsland CP. Plasma concentrations after high dose (45 mg/kg) rectal acetaminophen in children.Canadian Journal of Anaesthesia 1995; 42: 982–986.
Anderson BJ, Woolard GA, Holford NH. Pharmacokinetics of rectal paracetamol after major surgery in children.Pediatric Anaesthesia 1995; 5: 237–242.
Autret E, Dutertre JP, Breteau Met al. Pharmakokinetics of paracetamol in neonate and infant after administration of propacetamol chlorhydrate.Deve Pharmacol Ther 1993; 20: 129–134.
Vetter TR, Heiner EJ. Intravenous ketorolac as an adjuvant to pediatric patient-controlled analgesia with morphine.Journal of Clinical Anesthesia 1994; 6(2): 110–113.
Buck ML. Clinical experience with ketorolac in children.Ann Pharmacother 1994; 28: 1009–1013.
Wachta MF, Jones MB, Laguereula RG, Schweiger L, White PF. Comparison of ketorolac and morphine as adjuvants during pediatric surgery.Anesthesiology 1992; 76(3): 368–372.
Sims C, Johnson CM, Bergesio R, Delfos SJ, Avraamides EA. Rectal indomethacin for analgesia after appendectomy in children.Anesthesia and Intensive Care 1994; 22: 272–275.
Mather SJ, Peutrell JM. Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques.Pediatric Anaesthesia 1995; 5(3): 185–188.
Humunen K, Maunuksela EL. Ketorolac does not depress ventilation in children. (Letter to the editor).Pediatric Anaesthesia 1996; 6: 79.
Houck CS, Wilder RT, McDermott JS, Berde CB. Safety of intravenous ketorolac in children and cost savings with a unit dosing system.Journal of Pediatrics 1996; 129: 292–296.
Buck ML, Norwood VF. Ketorolac induced acute renal failure in a previously healthy adolescent.Pediatrics 1996; 98: 294–296.
Tyler DC. Pharmacology of pain management. In: Wetzel R, ed.Pediatric Clinics of North America, Vol. 41, Philadelphia: W.B. Saunders, 1994: 59–71.
Doyle E, Morton NS, McNichol LR. Comparison of Patient-controlled analgesia in children by i.v. and s.c. routes of administration.Brit J of Anaesth 1994; 72: 533–536.
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Berkowitz, R.A., McDonald, T.B. Post-operative pain management. Indian J Pediatr 64, 351–367 (1997). https://doi.org/10.1007/BF02845204
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DOI: https://doi.org/10.1007/BF02845204