Skip to main content
SpringerLink
Log in

Kinetics of oxidation of glycylglycine by bromamine-T in acid medium

  • Published:
Proceedings of the Indian Academy of Sciences - Chemical Sciences Aims and scope Submit manuscript

Abstract

The kinetics of oxidation of a typical dipeptide glycylglycine (GG) by bromamine-T have been studied in HClO4 medium at 40°C. The rate shows first-order dependence on [BAT]0 and is fractional order in [GG]0 which becomes independent of [substrate]0 at higher [GG]0. At [H+ ] > 0.02mol dm−3, the rate is inverse fractional in [H+ ] but is zero order at lower [H+ ] (≤0.02 mol dm−3). Variation in ionic strength or dielectric constant of the medium had no significant effect on the rate. The solvent-isotope effect was measured and\(k'_{H_2 O} /k'_{H_2 O} \)= 1.45. Proton inventory studies have been made. The reaction has been studied at different temperatures (308-323 K) and activation parameters have been computed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Akabori S, Narita K, Toki K and Hanafusa H 1954J. Chem. Soc. Jpn., Pure Chem. Sec. 75 782

    Google Scholar 

  • Amis E S 1966Solvent effects in reaction rates and mechanisms (New York: Academic Press)

    Google Scholar 

  • Bishop E and Jennings V J 1958Talanta 1 197

    Article  CAS  Google Scholar 

  • Collins C J and Bowman N S 1970Isotope effects in chemical reactions (New York: Van Nostrand) p. 267

    Google Scholar 

  • Feigl F 1956Spot tests in organic analysis (Amsterdam: Elsevier) p. 341

    Google Scholar 

  • Fieser L F and Fieser M 1958Organic chemistry (Boston: D C Heath) p. 426

    Google Scholar 

  • Hammel E F Jr and Glasstone S 1954J. Am. Chem. Soc. 76 3741

    Article  CAS  Google Scholar 

  • Haurowitz F 1950Chemistry and biology of proteins (New York: Academic Press)

    Google Scholar 

  • Issacs N S 1987Physical organic chemistry (Belfast: Longmans) p. 275

    Google Scholar 

  • Laidler K J 1973Chemical kinetics (New Delhi: Tata-McGraw Hill) p. 227

    Google Scholar 

  • Mahadevappa D S, Ananda S, Murthy A S A and Rangappa K S 1983Reaction Kinet. Catal. Lett. 23 181

    Article  CAS  Google Scholar 

  • Mahadevappa D S, Ananda S, Murthy A S A and Rangappa K S 1984Indian J. Chem. A23 17

    Google Scholar 

  • Mahadevappa D S and Gowda N M M 1975Talanta 22 771

    Article  CAS  Google Scholar 

  • Martin R J L 1955Nature (London) 771

  • Nair C G R and Indrasenan P 1976Talanta 23 239

    Article  CAS  Google Scholar 

  • Rangappa K S, Mahadevappa D S, Gowda B T and Gowda N M M 1981Microchem. J. 26 375

    Article  CAS  Google Scholar 

  • Synge R L M 1945Biochem. J. 39 351

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Studies in Chemistry, University of Mysore, Manasagangotri, 570 006, Mysore, India

    T. Asha Iyengar & D. S. Mahadevappa

Authors
  1. T. Asha Iyengar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. S. Mahadevappa
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Iyengar, T.A., Mahadevappa, D.S. Kinetics of oxidation of glycylglycine by bromamine-T in acid medium. Proc. Indian Acad. Sci. (Chem. Sci.) 105, 63–70 (1993). https://doi.org/10.1007/BF02841351

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02841351

Keywords

Search

Navigation