Abstract
The contraceptive efficacy and local effects of bioceramic IUD in rat were studied. The experiment was divided into four groups: bioceramic IUD group; stainless steel IUD group; operation control group; normal control group. All IUD samples were put into uterus of rats. The experimental results show that the alumina bioceramic has a strong contraceptive effect for those rats. In bioceramic IUD group the endometrial inflammation reaction was as mild as that in stainless IUD group during the early days (30 days) and gradually abated with time during the late days (60 days). The experiments show that the alumina bioceramic has a good biocompatibility and contraceptive effects and hint at the alumina bioceramic IUD may become a more safety reproduction family planning IUD.
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Funded by the Education Office of Hubei Province of China (No. 98D006)
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Yan, W., Yuanzhen, Z., Yuhua, Y. et al. Contraceptive efficacy and local effects of bioceramic IUD in rat. J. Wuhan Univ. Technol.-Mat. Sci. Edit. 21, 99–101 (2006). https://doi.org/10.1007/BF02841215
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DOI: https://doi.org/10.1007/BF02841215