Skip to main content
SpringerLink
Log in

Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy

  • Clinical Experiences
  • Published:
Chinese Journal of Integrative Medicine Aims and scope Submit manuscript

Abstract

Objective: To observe the effect of Ginkgo biloba extract injection (GB) in treating early diabetic nephropathy (DN).Methods: Sixty DN patients were divided into two groups, the treated group were treated by GB and Western medicine, and the control group were given Western medicine alone. The study lasted for 4 weeks. Fasting plasma glucose (FPG), blood pressure, 24 h urinary albumin excretion (UAE), endogenous creatinine clearance rate (Ccr), blood lipids and hemorheology indices were examined before and after the study. Results: Compared with the control group, UAE were significantly decreased (P<0. 01); Ccr, blood lipids and hemorheology indices were all improved after treatment in the treated group (P< 0.05 orP<0.01). But in FPG and blood pressure there was no significant change between the treated group and the control group (P>0.05).Conclusion: GB is effective in treating early DN through decreasing urinary albumin excretion rate, regulating blood lipids, improving renal function and hemorheology.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Pan CY, Jin WS. Strengthening the screening of trace albuminuria, to elevate the level of preventing and treating diabetic nephropathy. Chin J Intern Med 2004; 43 (3): 161–162.

    Google Scholar 

  2. Wolf G. Cell cycle regulation in diabetic nephropathy. Kidney Int 2000; 58(suppl 77): 59–68.

    Article  Google Scholar 

  3. Kang H, Huang M. Ginkgo biloba leaf extract pharmacologic study survey. J Pharm Practice 2002; 20 (6): 334–338.

    Google Scholar 

  4. Liao P, Wang SQ, Liao XS, et al. Experimental study of Ginkgo biloba leaf extract on DM rats’ nephroprotection. Chin Pharmacy 2000; 11 (3): 114–115.

    Google Scholar 

  5. Tang JH, Xu QR, Liu TL, et al. Experimental study on Ginkgo biloba leaf preventing and treating glomerulosclerosis and tubulo-interstitial injury. Chin J Nephrol 1998; 14 (3): 174–176.

    Google Scholar 

  6. Zhao J, Wang JJ, Liu YF. Effect of Ginkgo biloba preparation on geriatric cerebral infarction accompanied DM patients hemorheology. Chin Microcirc 2002; 6 (4): 218–219.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Nephrology, Affiliated Hospital of Guangdong Medical College, 524001, Zhanjiang

    Lu Jie

  2. The First Central Hospital of Tianjin, China

    He Hai

Authors
  1. Lu Jie
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. He Hai
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jie, L., Hai, H. Clinical observation of Gingko biloba extract injection in treating early diabetic nephropathy. Chin. J. Integr. Med. 11, 226–228 (2005). https://doi.org/10.1007/BF02836510

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02836510

Key words

Search

Navigation