Abstract
Twelve children were admitted with convulsions and altered sensorium following ingestion of locally obtained neem oil. Ten died within 24 hours. Of the six children investigated completely, four showed significant acidosis and all showed significant rise in serum transaminases suggesting liver damage. All had normal CSF values. Liver biopsy done in one showed fatty degeneration.
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References
Kirticar KR, Basu BD: Azadirachta India Vol. 1. Indian Medicinal Plants. P 536 II Ed. Published by Lalitha Mohan Basu, Allahabad. 1935
Bhide NK; Toxicity of sodium nimbudinate Indian J Med Sc 12: 146, 1650
Nadkarni AK: Indian Materia Mcdica. 3rd Edn. Popular Book Depot. Bombay 1961
Hildrich LP, Murty KS: Composition of Neem Oil. J Sec chem Ind 58: 310, 1933
Suryanarayanamoorthy P, Sirsi M: Pharmacological studies on Melia Azadiracta toxicity and pharmacodynamic actions of neem oil, nimbidin and nimbidel. Indian Med Record 82: 70, 1962
Vijayalakshmi B: Toxicity of Neem Oil. Proceedings of the National Conference of Physiology. 1979. (Personal communication)
Baskaran DSG: Neem oil poisoning as a cause of Reye’s syndrome in Malaysia. April 1981 (Personal communication)
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Sundaravalli, N., Raju, B.B. & Krishnamoorthy, K.A. Neem oil poisoning. Indian J Pediatr 49, 357–359 (1982). https://doi.org/10.1007/BF02834422
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DOI: https://doi.org/10.1007/BF02834422