Abstract
Endemic goitre due to iodine deficiency is a health problem that afflicts, with varying degrees, of severity, an estimated 40 million people throughout the subcontinent. In areas where goitre prevalence is high (more than 50%) major attendant disabilities of endemic goitre such as endemic cretinism, deaf—mutism and feeble mindedness are present in about 4% of the population.
Iodisation of salt can be an effective prophylactic measure against goitre. Though, a National Goitre Control Programme was launched 2 decades back, only less than 15% of the known goitrous areas have been covered by the programme (1979–80). The major constraints in this regard seem to be inadequate availability of iodised salt.
Urgent implementation of iodine prophylaxis is imperative. Also, the benefits of modern technological advancement for early detection and prompt treatment of thyroid related developmental abnormalities of the brain among the new borns in these areas, should be utilised as an interim measure to prevent further such damages.
References
Ramalingaswami V, Subramanyam TAV, Deo MG: The etiology of Himalayan endemic goitre. Lancet i: 791, 1961
Kochupillai N, Philip Augustine, Ahuja MMS: Quantitative aspects of iodine metabolisum in simple goitre seen in Delhi and neighbourhood areas. J All India Institute of Medical Sciences 3: 159, 1977
Pandav CS, Kochupillai N, Karmarkar MG, Ramachandran K, Gopinath PG, Nath LM: Endemic goitre in Delhi. Ind J Med Res 72:81,1980
Sooch SS, Deo MG, Karmarkar MG, Kochupillai N, Ramachandran K, Ramalingaswami V: Prevention of endemic goitre with iodized salt. Bull WHO 49: 307, 1973
Country Programme People, National Goitre Control Programme, Government of India, September 1980.
Langer P: Endemic Goitre, Monograph Series No. 44 World Health Organization. Geneva 1960 p 10
Ramalingaswami V: Endemic goitre in South East Asia—New clothes on an old body. Ann Int Med 78: 277,1973
Kelly FC, Snedden WW: Endemic Goitre. Monograph Series No. 44. World Heath Organization. Geneva. 1960. p. 27
Kelly FC, Snedden WW: Endemic Goitre. Monograph Series No. 44. World Health Organization. 1960. p. 156
Sengupta SK, Kapoor PN, Roychoudhary SK: Prevalence of Endemic Goitre on the Sub-Himalayan Range of India. Ind J Med Res 56: 1423, 1968
Pocket Book of Health Statistics of India. Central Bureau of Health Intelligence, Directorate General of Health Services, Ministry of Health and Family Welfare, Goverment of India. 1978 and 1980
Edibam HH, Dave BT, Niyogi AK: Endemic goitre in Narmada valley in Broach district, Gujrat. Ind J Med Sc 26: 218, 1972
Dandare MP, Sathe PV: A goitre survey in school children in Sillod Taluka, Aurangabad district, Maharashtra. Ind J Pre Soc Med 4: 47,1973
Krishnamachari KA: Endemic goitre. a public health problem in Maharashtra, Ind. Trop Geogr Med 26: 147, 1974
Sathe PV, Dandare MP: Goitre survey in Sillod Taluka, Aurangabad District, Maharashtra State. Ind J Pub Health 19: 84, 1975
Karmarkar MG: Personal Communication
Basu PK, Narayan R, Yusuf S, James KK: Preliminary report of survey of prevalence of goitre in Tea estates of Munnar. Paper presented at VIth All India Conferences of Preventive & Social Medicine. Bangalore 1976
Dwivedi MP: Survey—sub-Vindhya belt of Endemic goitre Swastha Hind. August: 186,1978
Dudani TG, Natu MN: Epidemiolcgy of goitre in Ghodegaon. Ind J Med Res 12; 980,1978
Trivedi DH. Shah DN, Vyas DB, Patel YI: Endemic goitre in the villages along the bank of river Karjan and Narmada of Broach District, Gujrat. Ind J Com Med IV: 23,1979
Shah DH: Goitre survey in the school children of Bombay. Current Thyroid Problems in Southeast Asia and Oceania; Asia and Oceania Thyroid Association, 1978
Karmakar MG, Deo MG, Kochupillai N, Ramalingaswami V: Pathophyiology of Himalayan endemic goitre. Am J Clin Nutr 27: 96, 1974
Sooch SS, Ramalingaswami V: Preliminary report of an experiment in the Kangra valley for the prevention of Himalayanendemic goitre with iodinated salt. Bull WHO 32: 229, 1965
Stanbury JB, Ermans AM, Hetzel BS, Pretell EH, Querido A: Endemic goitre and cretinism—public health significance and prevention. WHO Chronicle 28: 220,1973
McCarrison R: The Etiology of Endemic Goitre. Lancet 219: 1913
Kelly FC, Snedden WW: Endemic Goitre. Monograph Series No. 44. World Health Organization. Geneva 1960. p 153
Ingenbleek Y, Luypaert B, Nayer Ph De: Nutritional status and endemic goitre. Lancet i: 388, 1980
Kochupillai N, Karmarkar MG, Weightman D, Hall R, Deo MG, McKendrick M, Everd DC, Ramalingaswami V: Pituitary thyroid axis in Himalayan endemic goitre. Lancet i: 1021,1973
Querido A, Delange F, Dunn T, Fienitez R, lbbertson HK, Koutras DA, Perinetti H: Definitions of endemic goitre and cretinisum, classification of goitre size and severity of endemics and survey techniques. PAHO Sci Pub no. 292, 1974, p 267
Thilly CH, Hetzel BS: An assessment of prophylactic programs In, Stanbury JB Hetzel BS (ed): A Willey Medical Publication. New York. New York. 1980; p 473
Lauder JM: Effects of thyroid state on development of rat cerebellar cortex. In, Grave GD (ed): Thyroid Hormones and Brain Development, Raven Press. New York. 1977. p 235
Raiti S, Newns GH: Cretinism: Early diagnosis and its relation to mental prognosis. Arch Dis Child 46: 692, 1971
Klein AH, Meltzer S. Kenny FM: Improved prognosis in congenital hypothyroidism treated before age three months. J Paediatr 89: 912,1972
Leading Articles: Screening for congenital hypothyroidism. Br Med J 281: 1, 1980
Dussault JH, Morissette J, Letarte J, Guyda H, Laberge C: Modification of a screening programme for neonatal hypothyroidism. J Paediatr 92:274, 1978
Mitchell ML, Larsen PR, Levy HL, Bennett AJE, Madoff M: Screening for congenital hypothyroidism. Results in the newborn population of New England. JAMA 239: 2348, 1978
Fisher DA, Dussault JH, Foley TP, Klein AH, LaFranchi S, Larsen PR, Mitchell ML, Murphey WH Walfish PG: Screening for congenital hypothyroidism: results of screening of one million North American infants. J. Paediatr 94:700, 1979
Lowenstein FW: Iodized salt in the prevention of endemic goitre. A world wide survey of present programs. Am J Pub Hlth 57:1815, 1967
Gopalan C, Rama Sastri BV, Balasubramanian SB: Nutritive value of Indian Foods, National Institute of Nutrition, Indian Council of Medical Recearch Hyderabad, India. Card Box Company Hyderabad. 1978, p. 23.
WHO: Report of a Seminar on Goitre Control. WHO, SEATO, New Delhi. 1967.
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Pandav, C.S., Kochupillai, N. Endemic goitre in India: Prevalence, etiology, attendant disabilities and control measures. Indian J Pediatr 49, 259–271 (1982). https://doi.org/10.1007/BF02830764
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DOI: https://doi.org/10.1007/BF02830764