Abstract
Poly(neutral red) film modified carbon fibre microelectrodes offer substantial improvement in voltammetric sensitivity and selectivity towards epinephrine (EP). The poly (neutral red) film was electropolymerized by cycling the potential between −0.8 V and +0.8 V. The anodic stripping voltammetric response for EP was found to be dependent on accumulation time and potential. By using a poly(neutral red) film modified carbon fibre microelectrode with a 1 min preconcentration at −1.2 V in biological phosphate buffer solution (pH=7.4). a good linear relationship between the anodic stripping peak currents and EP concentrations was obtained in the range of 2.0×10−7⊂2.0×10−5 mol/L. The detection limit was up to 9.0 ×10−8 mol/L. Moreover, 400 times higher concentrations of vitamin C did not interfere with the measurement of EP. This method was used for determining EP concentrations in epinephrine hydrochloride injection solution with satisfactory results.
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Supported by the National Natural Science Foundation of China
Tang Xiaorong: born in 1974, Master
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Xiaorong, T., Yuanxi, S., Bing, Y. et al. Determination of epinephrine using poly (neurtral red) modified carbon fibre microelectrodes by anodic stripping voltammetry. Wuhan Univ. J. Nat. Sci. 2, 479–483 (1997). https://doi.org/10.1007/BF02830263
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DOI: https://doi.org/10.1007/BF02830263