Abstract
A possibility of preparation of enantiomerically pure 1,1′-bi-2-naphthols using an impure cinchonine has been examined. The solid and the mother liquor formed from the reaction of 1,1′-bi-2-naphtholboric anhydride and 85% cinchonine in toluene could give optically pure (S)-(−)- and (R)-(+)-1,1′-bi-2-naphthol after acidification and kinetic crystallization, the overall yields were 40% and 28%, respectively.
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Supported by the National Natural Science Foundation of China (2937206) and the Natural Science Foundation of Hubei Province (93J27)
Xiong Ying, born in 1971, Graduate student
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Ying, X., Zixing, S., Fuyong, C. et al. Preparation of enantiomerically pure 1,1′-bi-2-naphthols from 85% cinchonine and 1,1′-bi-2-naphtholboric anhydride. Wuhan Univ. J. Nat. Sci. 3, 345–347 (1998). https://doi.org/10.1007/BF02829991
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DOI: https://doi.org/10.1007/BF02829991