Summary
In order To evaluate whether the parameters of spiral artery blood flow, as measured by transvaginal color Doppler, may be used to assess endometrium receptivity prior to embryo transfer (ET), a retrospective study of 94 infertile women who had undergone ART treatments with different outcomes (pregnant or nonpregnant) was done. Subendometrial blood flow was evaluated. The resistance index (RI), systolic/diastolic ratio (S/D) and pulsatility index (PI) were significantly lower in those who achieved pregnancy as compared with those who did not: 0.62±0.04 vs 0.68±0.04. (P<0.001), 2.66±0.33 vs 3.19±0.39 (P<0.01) and 1.15±0.17 vs 1.34±0.22 (P<0.05), respectively. Furthermore, when RI>0.72,PI>1.6, and S/D>3.6, no pregnancy occurred. These data suggest that the parameters of spiral artery blood flow could be used as a new assay in predicting endometrial receptivity before ET.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Raga F, Bonilla-Musoles F, Casa E Met al. Assessement of endometrial volume by three-dimensional ultrasound prior to embryo transfer: Clues to endometrial receptiveity. Hum Reprod, 1999, 11: 2851
Gong X H, Le G R, Zhang Q Pet al. Application of transvaginal color Doppler in in-vitro fertilization and embryo transfer (Chinese), 2001, 8: 499
Gonen Y, Casper R F, Jacobson Wet al. Endometrial thickness and growth during ovarian stimulation: a possible predictor of implantation in IVF. Fertil Steril, 1989, 52: 446
Goswamy R K, Steptoe P C. Doppler ultrasound studies of the uterine artery in spontaneous ovarian cycles. Human Reprod, 1988, 3: 721
Kurjak A, Kupesic S, Schulman Het al. Transvaginal color flow Doppler in the assessment of ovarian and uterine blood flow in infertile women. Fertil Steril, 1991; 56: 870
Sterzik K, Htter W, Grab Det al. Doppler sonographic findings and their correlation with implantation in an IVF program. Fertil Steril, 1989, 52: 825
Steer C V, Mills C, Campbell Set al. The use of transvaginal color flow imaging after IVF to identify optimum uterine conditions before embryo transfer. Fertil Steril, 1992, 57: 372
Kupesic S, Kurjak A. Uterine and ovarian perfusion during the periovulatory period assessed by transvaginal color Doppler. Fertil Steril, 1993, 60: 439
Yaron Y, Kogosowski A, Botchan Aet al. Endometrial receptivity: the age-related decline in pregnancy rates and the effect of ovarian function. Fertil Steril, 1993, 60: 314
Goswamy R K, Steptoe P C. Decreased uterine perfusion: a cause of infertility. Human Reprod, 1988, 3: 955
Cacciatore B, Simberg N, Fusaro P Aet al. Transvaginal Doppler study of uterine artery blood flow in in vitro fertilization cycles. Fertil Steril, 1996, 66: 130
Author information
Authors and Affiliations
Additional information
GONG Xuehao, male, born in 1970, M.D., Ph.D.
Rights and permissions
About this article
Cite this article
Xuehao, G., Quangshui, L., Qingping, Z. et al. Predicting endometrium receptivity with parameters of spiral artery blood flow. Current Medical Science 25, 335–338 (2005). https://doi.org/10.1007/BF02828160
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02828160