Summary
The commonest mailgnant conditions in childhood ate Hodgkin’s disease, acute lymphatic leukaemia, retinoblastoma and Wilm’s tumour. Malignancy is commoner in boys. No definite factor responsible for the causation of malignancy could be ascertained. Only in one case of Hodgkin’s disease a familial incidence was found Thyroid enlargement was present a incase of acute lymphocytic leukaemia which regressed along with the primary disease on treatment. The longest survival time of a case of Hodgkin’s disease was 5 years and of chronic myeloid leukaemia, 51/2 years. This study has also revealed that one has to collect data from various hospitals in order to know the type of malignancies prevalent in childhood, as cases with only a particular type of malignant disease are admitted to children’s hospital
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References
Carter, C.O. (1958). A life table for mongols with the causes of death,J. of Ment. Defici. Res. 2, 64.
Falls, H.F. and Nell, J.V. (1952). Genetics of retinoblastoma.Arch. Ophth.,46, 367.
Ghai, O.P. Ketrapal, S.K. and Walia, B.N.S. (1962). Leukaemia in childhood.Indian J. Pediat. 29, 405.
Gross, R.E., (1953). Wilms Tumour. The Surgery of Infancy and Childhood, Chapter 45.
Gioss, R.E., Farber,S. and Martin, L.W. (1959). Neuroblastoma sympatheticum. A study and report of 217 cases.Pediatrics,23, 1179.
Krivit, W. and Good, R.A. (1952). Simultaneous occurrences of mongolism and leukaemia — A report of a nationwide survey.Amer. J. Dis. Child. 94, 289.
Kwan-Yuen Wong, Irwin B, Hanson&, Lieatric C. Lampkin (1971). Familial neuroblastoma,Amer. J. Dis. Child. 121, 415.
Manchanda, S.S.. (1960). Leukaemia in children.Indian Pract. 13, 649.
Nelson, W.E. (1969). Text-book of Pediatrics Page 1436–1477 9th Edition.
Peterson, R.D.A., Cooper, M.D. and Good, R.A. (1965). Disorders of the thymus and other lymphoid tissue.Progress in Med. Genet4, 1.
Shrikhande, S.S. and Sirsat, M.V. 1966–67). Retinoblastoma in Indians. Year Book of Cancer, Page 234.
Steward, J.K. (1958). Malignant diseases, Modern Trends In Paediatrics (Second series) Page, 162.
Udani, P.M. (1961). Clinical manifestations of leukaemia in children.Indian J. Child. Hlth.,10, 169.
Vidyasagar Rao, K., Govind Rao, G. K., Tulasi, C., Reddi, Y.R. and Chandra, H. (1971). Leukaemia in children.Indian Pediat. 8, 388.
Weiler, C.V. (1941), The inheritance of retinoblastoma and its relationship to practical eugenics.Cancer Res. 1, 517.
Wells, H.G. (1940). Occurrence and significance of congenital malignant neoplasms.Arch. Path. 30, 35
Willionghy, M L.N. (1968). Cyclic therapy in childhood acute leukaemia.Arch. Dis. Child. 43, 187.
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Jain, K.K., Mathur, G.P. & Srivastava, J.R. Malignancy in childhood. Indian J Pediatr 42, 61–66 (1975). https://doi.org/10.1007/BF02827984
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DOI: https://doi.org/10.1007/BF02827984