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Precocious pseudopuberty with testicular enlargement

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Abstract

Gonadotropins independent precocious puberty (GIPP) in male is characterized by early appearance of sexual hairs and phallic growth but without testicular enlargement. We report a case of GIPP with testicular enlargement who was diagnosed to have testotoxicosis and successfully managed with spironolactone.

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References

  1. Kaplowit PB, Oberfield SE. Reexamination of age limit for defining when puberty is precocious in girls in United States: implications for evaluation and treatment. Drug and Therapeutic and Executive Committees of the Lawson Wilkins Pediatric Endocrine Society.Pediatrics 1999; 104: 936–941.

    Article  Google Scholar 

  2. Marke DP, Cutler GB Jr. Evaluation and management of Precocious puberty.Arch Dis Child 1996: 296–371.

  3. Low LC, Wang Q: Gonadotropin indepaendent precocious puberty.J Pediatr Endocrinol Metab 1998: 497–507.

  4. Melvin M Grumbach, Dennis MStyne. Puberty: Ontogeny, meuroendocronology, physiology and disorders. In Larsen, Kronenberg, Metmed, polonsky, eds.Williams's textbook of Endocrinology. Philadelphia; WB Saunders, 2003; 1219–1221.

    Google Scholar 

  5. Egli CA, Rosenthal SM, Grumbach MMet al. Pituitiary gonadotropin-independent male-limited autosomal domonant sexual precocity in nine generations: familial testotoxicosis.Arch Pathol Lab Med 1985; 109: 990–995.

    PubMed  Google Scholar 

  6. Shenker A, Laue L, Kosugi Set al. A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty.Nature 1993; 365: 652–654.

    Article  PubMed  CAS  Google Scholar 

  7. Laue L, Kenigsberg D, Pescovitz OH. Treatment of familial male precocious puberty with spironolactone and testolactone.N Engl J Med 1989; 320: 498–502.

    Article  Google Scholar 

  8. Leschek EW, Jones J, Barnes KMet al. Six year results of spironolactone ans testolactone treatment of familial male-limited precocious puberty with addition of deslorelin after central puberty onset.J Clin Endocrinol Metab 1999; 84 (1): 175–178.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Endocrinology, Postgraduate Institute of Medical, Education and Research, 160012, Chandigarh, India

    R. Rajput, A. Bhansali, R. Bhat & R. Sialy

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  1. R. Rajput
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  2. A. Bhansali
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  3. R. Bhat
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  4. R. Sialy
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Corresponding author

Correspondence to A. Bhansali.

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Rajput, R., Bhansali, A., Bhat, R. et al. Precocious pseudopuberty with testicular enlargement. Indian J Pediatr 73, 356–358 (2006). https://doi.org/10.1007/BF02825833

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  • DOI: https://doi.org/10.1007/BF02825833

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