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Reyes’s syndrome in Delhi

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Abstract

Reye’s syndrome was diagnosed in about 15% of cases of encephalopathy syndrome admitted in hospital. Hypoglycemia, considered a hallmark of the disease, was an uncommon observation particularly in patients beyond one year of age (8.5%). Transaminases were more useful than hypoglycemia for suspecting this syndrome (raised in 80% of cases). Progression of the disease was very rapid. The existing management is very unsatisfactory. 11 out of 12 cases died. A high order of suspicion in a patient who presents with vomiting, hepatomegaly and sensorial obtundation is proposed for early diagnosis.

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Kalra, V., Sachdev, H.P.S. & Menon, P.S.N. Reyes’s syndrome in Delhi. Indian J Pediatr 48, 585–588 (1981). https://doi.org/10.1007/BF02821577

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