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Efficacy of caudal butorphanol

The Indian Journal of Pediatrics volume 73, pages 147–150 (2006)Cite this article

Abstract

Objective: To evaluate the efficacy of butorphanol with or without bupivacaine for caudal epidural anesthesia in children undergoing infraumbilical surgery.Methods: Sixty ASA physical status I and II patients of either sex aged 1–10 yr were randomized to one of three groups. Group L received 1 ml/kg of 0.25% bupivacaine; Group B received 1 ml/kg of 25 μg/kg butorphanol diluted in normal saline; and Group LB received 1 ml/kg of 25 μg/kg butorphanol in combination with 0.25% patients. Sedation score, pain score, and requirement of rescue analgesia were recorded at preset time intervals alongwith postoperative complications.Results: There was no difference among the groups regarding sedation scores, requirement of rescue analgesia and post-operative complications. Mean duration of analgesia was maximum in group BL (14.5±3.5 hr, P<0.001), than in group L (8.8±4.8 hr) and group B (6.8±2.9 hr).Conclusion: The, addition of 25 μg/kg butorphanol to bupivacaine resulted in superior analgesia with a longer period compared with caudal bupivacaine and butorphanol alone, without an increase of side effects.

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References

  1. Anand KJ, Coskun V, Thrivikraman KVet al. Long-term behavioral effects of repetitive pain in neonatal rat pups.Physiol Behav 1999; 66: 627.

    PubMed  Article  CAS  Google Scholar 

  2. Dalens B.Regional anesthesia in infants, children and adolescents. 2nd ed. London, Baltimore; Williams and Wilkins, Waverly Europe, 1995.

    Google Scholar 

  3. Wolf AR, Hughes D, Wade A, Mather SJ, Prys-Roberts C. Postoperative, analgesia after pediatric orchiopexy: evaluation of a bupivacaine morphine mixture.British J Anesthesia 1990; 64: 430–435.

    Article  CAS  Google Scholar 

  4. Senel AC, Akyol A, Dohman D, Solak M. Caudal bupivacaine-tramadol combination for postoperative analgesia in pediatric herniorrhaphy.Acta Anesthesiol Scand 2001; 45 (6): 786–789.

    Article  CAS  Google Scholar 

  5. Lawhorn CD, Stoner JM, Schmitz ML, Brown RE Jr, Stewart FW, Volpe P, Shirey R. Caudal epidural butorphanol plus bupivacaine versus bupivacaine in pediatric outpatient genitourinary procedures.J Clin Anesth 1997; 9 (2): 103–104.

    PubMed  Article  CAS  Google Scholar 

  6. Ohta K, Katsuno M, Kawana S, Namiki A. Epidural opioids for post-operative pain control in pediatric patients with cerebral palsy.Masui 1993; 42(5): 664–668.

    PubMed  CAS  Google Scholar 

  7. Sung Y-F, Weinstein MS, Ghani GA. Balanced anesthesia: A comparison of butorphanol and morphine.Southern, Medical Journal 1984; 77: 180–182.

    CAS  Google Scholar 

  8. Abdoud TK, Moore M, Zhu J, Murakawa Ket al. Epidural butorphanol or morphine for the relief of postcesarean section pain: ventilatory responses to, carbon dioxide.Anesth Analg 1987; 66: 887–893.

    Google Scholar 

  9. Bromage PR, Campresi EM, Durant PAC, Nielsen CH. Rostral spread of epidural morphine.Anesthesiology 1982; 56: 431–436.

    PubMed  Article  CAS  Google Scholar 

  10. Allan CY, Jacqueline PA, Shubhda JH. Caudal epidural blockversus other methods of postoperative pain relief for circumcision in boys.Cochrane, Database Syst Rev 2003; (2): CD 003005.

  11. Gaitini LA, Somri M, Vaida SJ, Yanovski B, Mogilner Get al. Does the addition of fentanyl to bupivacaine in caudal epidural block have an effect on the plasma level of catecholamines in children?Anesth Analg 2000; 90 (5): 102–133.

    Article  Google Scholar 

  12. Prosser DP, Davis A, Booker PD, Murry A. Caudal tramadol for postoperative analgesia in pediatric hypospadias surgery.Br. J Anaesth 2000; 85 (5): 805–807.

    Google Scholar 

  13. Lee JJ, Rubin AP. Comparison of a bupivacaine—clonidine mixture with plain bupivacaine for caudal analgesia in children.Br J Anesth 1994; 72: 258–268.

    Article  CAS  Google Scholar 

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  1. Assistant Professor, Department of Anesthesiology, King George’s Medical University, 226014, Lucknow, U.P., India

    Vinita Singh, Ashish Kanaujia & G. P. Singh

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  1. Vinita Singh
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  2. Ashish Kanaujia
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  3. G. P. Singh
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Correspondence to Vinita Singh.

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Singh, V., Kanaujia, A. & Singh, G.P. Efficacy of caudal butorphanol. Indian J Pediatr 73, 147–150 (2006). https://doi.org/10.1007/BF02820207

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  • DOI: https://doi.org/10.1007/BF02820207

Key words

  • Pediatric surgery
  • Caudal epidural anesthesia
  • Butorphanol
  • Bupivacaine