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l-proline as a nitrogen source increases the susceptibility ofSaccharomyces cerevisiae S288c to fluconazole

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Abstract

Fluconazole inhibition ofSaccharomyces cerevisiae S288c growth was evaluated in media containing ammonia,l-proline orl-leucine as a nitrogen source. Growth inhibition by fluconazole was maximum whenl-proline was used as a nitrogen source, while rhodamine 6G accumulation and fluconazole resistance were the highest when ammonia was the sole nitrogen source.

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Authors and Affiliations

  1. Biochemistry Department, School of Medicine, Buenos Aires University, Argentina

    C. A. Stella, R. Costanzo, H. I. Burgos, D. A. Saenz & R. D. Venerus

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  1. C. A. Stella
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  2. R. Costanzo
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  3. H. I. Burgos
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  4. D. A. Saenz
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  5. R. D. Venerus
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Correspondence to C. A. Stella.

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Stella, C.A., Costanzo, R., Burgos, H.I. et al. l-proline as a nitrogen source increases the susceptibility ofSaccharomyces cerevisiae S288c to fluconazole. Folia Microbiol 43, 403–405 (1998). https://doi.org/10.1007/BF02818581

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  • DOI: https://doi.org/10.1007/BF02818581

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