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The cyclosporins

Abstract

This review presents the progress and some aspects achieved during recent years with cyclosporin sources, chemistry, biological activities, side effects, biosynthesis and metabolism. Although incomplete the results indicate future research trends and some white spots to be studied in the near future to afford unique insights into cell biology and to improve the search for similar and even more specific agents based on rational drug design.

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Řeháček, Z. The cyclosporins. Folia Microbiol 40, 68–88 (1995). https://doi.org/10.1007/BF02816529

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  • DOI: https://doi.org/10.1007/BF02816529

Keywords

  • Cyclophilin
  • MeVal
  • Tolypocladium Inflatum
  • Amino Acid Reabsorption