Abstract
Two synthetic 2,6-disubstituted 4-anilinoquinazolines exerted a significant effect on the G+ bacteriaBacillus subtilis andStaphylococcus aureus. None of 12 tested derivatives influencedEscherichia coli, Proteus mirabilis andPseudomonas aeruginosa. Derivatives having the aromatic ring non-substituted or substituted by bromine, the pyrimidine ring by phenyl, morpholine or piperidine and the aniline skeleton non-substituted or substituted by methyl or amino group exterted a considerable antibacterial activity.
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Gottasová, R., Kubíková, J. & Čipák, L. Antibacterial effect of some 2,6-disubstituted 4-anilinoquinazolines. Folia Microbiol 43, 679–682 (1998). https://doi.org/10.1007/BF02816389
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DOI: https://doi.org/10.1007/BF02816389