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Ciliostatic effect of fungi on the respiratory tract ciliary movement of one-day-old chickensin vitro

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Abstract

The ciliostatic activity of exo- and endometabolites of 243 filamentous fungal strains was evaluated byin vitro bioassay using tracheal organ cultures of 1-d-old chicks. Chloroform-extractable metabolites produced in the cultivation medium (25°C/10 d) by 30 out of 72 (41%) investigated strains displayed the ciliostatic activity as did metabolites from the biomass of the spores and the mycelium of 46 other strains (26%). This result could contribute to the clarification of the correlation between fungi and respiratory disorders in some working places and in damp dwellings.

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Piecková, E., Jesenská, Z. Ciliostatic effect of fungi on the respiratory tract ciliary movement of one-day-old chickensin vitro . Folia Microbiol 41, 517–520 (1996). https://doi.org/10.1007/BF02814671

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