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Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor

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Abstract

DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing)Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.

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Šmardová, J., Spížek, J., Šťastná, J. et al. Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor . Folia Microbiol 34, 536–538 (1989). https://doi.org/10.1007/BF02814465

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