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Thyroid hormone-protein interactions in active thyroid immunity

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From the Veterans Administration Hospital, Jefferson Barracks and Washington University, St. Louis, Missouri, U. S. A.

The investigations reported herein were partially supported by grants from the National Institutes of Health, Bethesda, Maryland.

Throughout this article the use of the expression ‘active immunity’ signifies artificial immunization, i.c., exogenous innoculation which is followed by antibody synthesisde novo. Active thyroid immunity, therefore, implies injection of an animal with thyroglobulin or other components of the thyroid tissue. In passive immunity there is no exogenous antigen challenge orde novo antibody synthesis, rather antibodies from an immune subject or an animal are merely transferred to another individual either naturally (e.g., passage of antibody gamma globulin, IgG, through the placenta) or artificially through exogenous administration.

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Premachandra, B.N. Thyroid hormone-protein interactions in active thyroid immunity. Indian J Pediatr 37, 295–304 (1970). https://doi.org/10.1007/BF02801343

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