Skip to main content
SpringerLink
Log in

Effect of diabetes on trace-element concentration of blood

  • Body Status from Trace Elements in Blood, Urine, Skin, and Hair
  • Published:
Biological Trace Element Research Aims and scope Submit manuscript

Abstract

The effect of diabetes on trace elements concentration in blood of experimental animals has been studied by thin-target X-ray fluorescence analysis. Balb/C young adult mice, 6–8 wk old, were used in the study. About 100–200 μL venous blood was taken from each mouse for trace element analysis. The measurements were carried out on a commercial Wave-Length-Dispersive XRF System, with different X-ray tubes being used for maximizing the detection sensitivity of different groups of elements.

Later on, the mice were made diabetic by an intravenous injection of Streptozotocin (250 mg/kg). Then, 2 and 3 wk after the injection, 100 μL of venous blood was drawn from each of the mice and analyzed for trace element concentration. In this way we were able to study the changes in blood trace elements caused by diabetes.

The results and advantages of using experimental animals, under controlled conditions, to study trace element variations caused by different diseases, are discussed in the paper.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Author information

Authors and Affiliations

  1. Department of Medical Physics, Austin Hospital, Melbourne

    M. A. Chaudhri & N. Noorbakhs

  2. University of Melbourne, Australia

    M. A. Chaudhri & N. Noorbakhs

  3. Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia

    M. Koulmanda

  4. Department of Geology, University of Melbourne, Melbourne, Australia

    M. T. Haukka

Authors
  1. M. A. Chaudhri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Koulmanda
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. T. Haukka
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Noorbakhs
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chaudhri, M.A., Koulmanda, M., Haukka, M.T. et al. Effect of diabetes on trace-element concentration of blood. Biol Trace Elem Res 12, 429 (1987). https://doi.org/10.1007/BF02796699

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02796699

Keywords

Search

Navigation