Summary
Five cases of anencephalic monsters, collected in 5 to 6 months have been dissected. The findings are compiled and presented.
All were female and more or less full term. The brain was grossly deformed in all. In one it was completely absent and in the other 4, it was present as a discoloured brown mass. The cerebellum in these latter 4 was reasonably well formed. The optic nerve and eyes were well developed in all.
The vault of the skull was deficient in all cases, from the supraorbital margin to the superior nuchal lines. The cervical spine was absent in 2, short in I, and defective posteriorly in the remaining 2.
The thymus was normal in 3, enlarged and bilobed in 2. The hypophysis was absent while the thyroid and adrenals were rudimentary.
All these cases were associated with certain other anomalies, the chief of which were pilonidal sinus, cystic kidneys, unicornuate uterus and malrotation of the gut.
The findings are discussed.
Similar content being viewed by others
References
Angevine D. M. (1938). Pathologic anatomy of hypophysis and adrenals in anencephaly.Arch. Path. 26, 507.
Bhargava, K. N., Garg, T. C. and Bhargava, S. N. (1961). An anencephalic monster with bilateral agenesis of kidney and other developmental errors.Curr. med. Pract. 5, 267.
Elliot T. R., and Armour, R. G. (1911). The development of cortex in the human suprarenal glands and its condition in hemicephaly.J. Path. Bact. 5, 481.
Ingalls, T. H., Curley, P. J. and Prindle, R. A. (1950). Anoxia as a cause of foetal death and defects in mouse.Amer. J. Dis. Child. 80, 34.
Manchanda, S. S. (1961). Anencephaly. A case report.Indian J. chld. Hlth. 10, 142.
Morgagni (1761). Quoted by Willis, R. A. and Potter, E. L., Pathology of Foetus and Infant. pp. 488–492, 1962Year Book Medical Publishers Inc. Chicago.
Stenberg, H. (1929). As quoted by R. A. Willis. Stowens, Daniel. Pediatric Pathology pp. 297, 298, 1959.Wilkins and Willins Co. Baltimore.
Vincent, C. (1957). The etiology of anencephaly.J. Obst. Gyn. brit. Emp. 60, 203.
Von Recklinghausen (1886). As quoted by Willis, R. A..
Willis, R. A. (1958). The Borderland of Embryology and Pathology. pp. 147–150, 1958.Butterworth & Co. (Publisher) Ltd. London.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bansal, P.C., Vare, A.M. & Indurkar, G.M. Anencephalic monsters. Indian J Pediatr 32, 197–201 (1965). https://doi.org/10.1007/BF02796285
Issue Date:
DOI: https://doi.org/10.1007/BF02796285