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Glutathione peroxidase activity, selenium, and lipid peroxide concentrations in blood from a healthy Polish population

I. Maternal and cord blood

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Abstract

Selenium (Se) concentrations in whole blood and plasma of 19 nonpregnant women. 14 mothers at delivery, 14 neonates, and 13 infants, aged 2–12 mo, were evaluated. The activity of glutathione peroxidase (GSH-Px) in erythrocytes and plasma and the level of lipid peroxides in plasma were also analyzed. Selenium concentrations in whole blood and plasma in mothers at delivery were significantly lower compared to nonpregnant women. Selenium concentrations in cord blood components were lower compared to mothers, but the differences were not significant. The concentration of the element decreased in the first few months of life. Glutathione peroxidase activity in erythrocytes differed only slightly in the examined groups. In plasma, however, the enzyme activity was significantly lower in pregnant compared to nonpregnant women and in neonates compared to their mothers. Lipid peroxide concentrations in plasma differed only slightly in the examined groups. The results obtained are discussed in terms of the observations of other investigators.

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Authors and Affiliations

  1. Department of Biochemistry, Medical Academy, Bydgoszcz, Poland

    Bronisław A. Zachara

  2. Department of Biochemistry, Institute of Agriculture, Bydgoszcz, Poland

    Bronisław A. Zachara

  3. Department of Biochemistry, Medical Academy, Łódź, Poland

    Wojciech Wąsowicz, Jolanta Gromadzińska & Maria Skłodowska

  4. Institute of Gynecology and Obstetrics, Medical Academy, Łódź, Poland

    Grzegorz Krasomski

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  1. Bronisław A. Zachara
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  2. Wojciech Wąsowicz
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  3. Jolanta Gromadzińska
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  4. Maria Skłodowska
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  5. Grzegorz Krasomski
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Zachara, B.A., Wąsowicz, W., Gromadzińska, J. et al. Glutathione peroxidase activity, selenium, and lipid peroxide concentrations in blood from a healthy Polish population. Biol Trace Elem Res 10, 175–187 (1986). https://doi.org/10.1007/BF02795616

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  • DOI: https://doi.org/10.1007/BF02795616

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