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Trace element content in fingernails and hair of a nonindustrialized US control population

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Abstract

The concentrations of 17 elements in the nail and hair of 117 subjects from a nonindustrialized environment were determined by instrumental neutron activation analysis (INAA). A new method of statistical treatment that allows for more meaningful use of detection limit values was used to process the concentration data. Geometric means and standard errors are presented for each element, along with a summary of the effects of age, sex, and treatment on the concentration of each element. For nails, these data represent the first comprehensive study for several important elements. Correlations for each element between hair and nail were determined. With few exceptions, concentrations of nonessential trace elements were positively correlated in hair and nail, whereas concentrations of essential elements showed no correlations. The factors affecting concentrations and control levels must be considered in studying alterations in disease states.

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Authors and Affiliations

  1. Department of Chemistry, University of Kentucky, 40506, Lexington, KY

    D. E. Vance, W. D. Ehmann & W. R. Markesbery

  2. Department of Neurology, University of Kentucky, 40506, Lexington, KY

    W. R. Markesbery

  3. Department of Pathology, University of Kentucky, 40506, Lexington, KY

    W. R. Markesbery

  4. Department of Sanders Brown Center on Aging, University of Kentucky, 40506, Lexington, KY

    W. D. Ehmann & W. R. Markesbery

Authors
  1. D. E. Vance
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  2. W. D. Ehmann
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  3. W. R. Markesbery
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Vance, D.E., Ehmann, W.D. & Markesbery, W.R. Trace element content in fingernails and hair of a nonindustrialized US control population. Biol Trace Elem Res 17, 109–121 (1988). https://doi.org/10.1007/BF02795450

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  • DOI: https://doi.org/10.1007/BF02795450

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