Abstract
Copper absorption was measured at two levels of dietary zinc in six healthy young men who were confined to a metabolic unit for a 75 d study of zinc utilization. A diet of conventional foods was fed, providing either 16.5 or 5.5 mg zinc and 1.3 mg copper daily. Copper absorption was determined by feeding65Cu, a stable isotope of copper, once during the 16.5 mg Zn diet and near the beginning and end of the 5.5 mg Zn diet. Apparent copper absorption averaged 48.1% when the 16.5 mg Zn diet was fed. This was significantly higher than the averages of 37.2 and 38.5% when the 5.5 mg Zn diet was fed. Absorption also differed significantly among subjects. Fecal copper did not differ between diets or among subjects. All subjects were in positive copper balance at both levels of dietary zinc. These results suggest that a dietary zinc intake slightly above the Recommended Dietary Allowance of 15 mg/d does not increase fecal copper loss and does not interfere with copper absorption.
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References
N. W. Solomons,Nutritional Bioavailability of Zinc, G. E. Inglett ed. ACS Symposium Series 210, American Chemical Society, Washington, DC, 1983, pp. 247–271.
A. Prasad, G. Brewer, E. Schoomaker, and P. Rabbani,JAMA 240, 2166 (1978).
T. U. Hoogenraad, R. Koevuet, and E. G. de Ruyter Korver,Eur. Neurol. 18, 205 (1979).
P. W. F. Fisher, A. Giroux, and M. R. L’Abbe,Am. J. Clin. Nutr. 40, 743 (1984).
National Research Council. Recommended Dietary Allowances, 9th ed., National Academy of Sciences, Washington, DC, 1980, pp. 151–154.
M. D. Festa, H. L. Anderson, R. P. Dowdy, and M. R. Ellersieck,Am. J. Clin. Nutr. 41, 285 (1985).
J. L. Greger, S. C. Zaikis, R. P. Abernathy, O. A. Bennett, and J. Huffman,J. Nutr. 108, 1449 (1978).
D. M. Burke, F. J. deMicco, L. J. Taper, and S. J. Ritchey,J. Gerontol. 36, 558 (1981).
J. L. Greger, P. Baligar, R. P. Abernathy, O. A. Bennett, and T. Peterson,Am. J. Clin. Nutr. 31, 117 (1978).
L. J. Taper, M. L. Hinners, and S. J. Ritchey,Am. J. Clin. Nutr. 33, 1077 (1980).
M. A. Colin, L. J. Taper, and S. J. Ritchey,J. Nutr. 113, 1480 (1980).
D. M. Hegsted,J. Nutr. 106, 307 (1976).
J. Turnlund, F. Costa, and S. Margen,Am. Clin. Nutr. 34, 2641 (1981).
L. Wada, J. R. Turnlund, and J. C. King,J. Nutr. 115, 1345 (1985).
S. J. Malawer and D. W. Powell,Gastroenterology 53, 250 (1967).
J. R. Turnlund, J. C. King, B. Gong, W. R. Keyes, and M. C. Michel,Am. J. Clin. Nutr. 42, 18 (1985).
J. R. Turnlund, N. Durkin, F. Costa, and S. Margen,J. Nutr. 116, 1239 (1986).
G. A. Milliken and D. E. Johnson,Designed Experiments, vol. 1. Lifelong Learning Publications, Belmont, CA. (1984).
M. Janghorbani, B. T. G. Ting, and V. R. Young,J. Nutr. 110, 2190 (1980).
J. R. Turnlund, M. C. Michel, W. R. Keyes, J. C. King, and S. Margen,Am. J. Clin. Nutr. 35, 1033 (1982).
P. E. Johnson,Stable Isotopes in Nutrition. J. R. Turnlund and P. E. Johnson, eds., ACS Symposium Series 258, American Chemical Society, Washington, DC 1984, pp. 139–156.
G. E. Cartwright and M. W. Wintrobe,Am. J. Clin. Nutr. 14, 224 (1964).
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Turnlund, J.R., Wada, L., King, J.C. et al. Copper absorption in young men fed adequate and low zinc diets. Biol Trace Elem Res 17, 31–41 (1988). https://doi.org/10.1007/BF02795445
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DOI: https://doi.org/10.1007/BF02795445