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Treatment of pancreatic cancer

Promises and problems of tamoxifen, somatostatin analogs, and gemcitabine

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Summary

The clinical problem posed by pancreatic cancer is introduced, and the epidemiology and pathology of the disease are briefly presented. The natural history of this tumor is then described in order to highlight the deficiencies of current therapeutic modalities. The extremely poor results of the drug trials are reviewed, followed by a detailed discussion and critique of the trials of novel treatments that include gemcitabine, somatostatin analogs, and tamoxifen. Finally, areas for future development are indicated.

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Rosenberg, L. Treatment of pancreatic cancer. Int J Pancreatol 22, 81–93 (1997). https://doi.org/10.1007/BF02787465

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