Medical Oncology

, Volume 15, Issue 4, pp 289–291 | Cite as

Systemic lupus erythematosus associated with primary large cell carcinoma of the lung

  • Hidemi Irie
  • Hiroaki SatohEmail author
  • Takao Akama
  • Yuko T Yamashita
  • Hiroichi Ishikawa
  • Morio Ohtsuka
Case Report


The association between systemic lupus erythematosus (SLE) and malignancy has been controversial in the literature. We report a case of lung cancer in a 50-year-old woman with a 4-year history of SLE. She underwent surgery at a pathological stage of T2N2M0, but she eventually died of rapid recurrence of the cancer in the abdomen resulting in massive haemorrhage from the inferior vena cava (IVC). Immunological disorders related to SLE are thought to contribute to rapid progression of the malignancy.


systemic lupus erythematosus lung cancer 


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Copyright information

© Stockton Press 1998

Authors and Affiliations

  • Hidemi Irie
    • 1
  • Hiroaki Satoh
    • 1
    Email author
  • Takao Akama
    • 2
  • Yuko T Yamashita
    • 1
  • Hiroichi Ishikawa
    • 1
  • Morio Ohtsuka
    • 1
  1. 1.Department of Respiratory Medicine, Institute of Clinical MedicineUniversity of TsukubaTsukuba City, IbarakiJapan
  2. 2.Department of Rheumatology, Institute of Clinical MedicineUniversity of TsukubaJapan

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